دورية أكاديمية
Decrease of estrogen receptors induced by 17 beta-estradiol and progesterone in cultured rabbit endometrial cells.
| العنوان: | Decrease of estrogen receptors induced by 17 beta-estradiol and progesterone in cultured rabbit endometrial cells. |
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| المؤلفون: | Murai JT, Lieberman RC, Yang JJ, Gerschenson LE |
| المصدر: | Endocrine research communications [Endocr Res Commun] 1979; Vol. 6 (3), pp. 235-47. |
| نوع المنشور: | Journal Article; Research Support, U.S. Gov't, P.H.S. |
| اللغة: | English |
| بيانات الدورية: | Publisher: Marcel Dekker Country of Publication: United States NLM ID: 0426337 Publication Model: Print Cited Medium: Print ISSN: 0093-6391 (Print) Linking ISSN: 00936391 NLM ISO Abbreviation: Endocr Res Commun Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: New York Ny : Marcel Dekker Original Publication: New York, Dekker. |
| مواضيع طبية MeSH: | Endometrium/*drug effects , Estradiol/*pharmacology , Progesterone/*pharmacology , Receptors, Estrogen/*drug effects, Animals ; Cells, Cultured ; Estradiol/metabolism ; Female ; Kinetics ; Methods ; Rabbits ; Receptors, Estrogen/analysis ; Receptors, Estrogen/metabolism |
| مستخلص: | A whole cell technique to measure estradiol receptors in cultured rabbit endometrial cells is described. The estradiol receptors measured appear to be composed of at least two components: one component has high affinity but low capacity, while the other component has low affinity but high capacity. Using the assay, the effects of estradiol and progesterone pretreatment were examined on the estradiol receptor levels. It was found that both of the hormones decreased the number of estrogen receptors in the cultured cells. The finding that estradiol decreased its own receptors was unexpected and its possible relevance is discussed. |
| المشرفين على المادة: | 0 (Receptors, Estrogen) 4G7DS2Q64Y (Progesterone) 4TI98Z838E (Estradiol) |
| تواريخ الأحداث: | Date Created: 19790101 Date Completed: 19800327 Latest Revision: 20191028 |
| رمز التحديث: | 20221208 |
| DOI: | 10.3109/07435807909061798 |
| PMID: | 520278 |
| قاعدة البيانات: | MEDLINE |
PDF full text from Publisher | تدمد: | 0093-6391 |
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| DOI: | 10.3109/07435807909061798 |