دورية أكاديمية
[Repair of bleomycin-induced damage to Escherichia coli DNA. II. Participation of inducible processes].
| العنوان: | [Repair of bleomycin-induced damage to Escherichia coli DNA. II. Participation of inducible processes]. |
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| عنوان ترانسليتريتد: | Reparatsiia indutsirovannykh bleomitsinom povrezhdeniĭ DNK u Escherichia coli. Soobshchenie II. Uchastie indutsibel'nykh protsessov. |
| المؤلفون: | Dzhataev SA, Tanirbergenov TB, Tarasov VA |
| المصدر: | Genetika [Genetika] 1980; Vol. 16 (10), pp. 1816-24. |
| نوع المنشور: | Comparative Study; Journal Article |
| اللغة: | Russian |
| بيانات الدورية: | Publisher: Izdatelstvo Nauka Country of Publication: Russia (Federation) NLM ID: 0047354 Publication Model: Print Cited Medium: Print ISSN: 0016-6758 (Print) Linking ISSN: 00166758 NLM ISO Abbreviation: Genetika Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: Moskva : Izdatelstvo Nauka |
| مواضيع طبية MeSH: | DNA Repair*, Bleomycin/*pharmacology , Escherichia coli/*genetics , Genes/*drug effects, Bacterial Proteins/biosynthesis ; DNA, Bacterial/radiation effects ; Drug Resistance, Microbial ; Enzyme Induction ; Escherichia coli/drug effects ; Mutation ; Species Specificity ; Ultraviolet Rays |
| مستخلص: | The role of inducible cell functions in repair and mutagenesis after bleomycin-induced DNA damages was studied in Escherichia coli. Influence on these processes of some rec genes as well as sbcB, the structural gene for exonuclease I, was investigated. The data obtained suggest that this enzyme plays a negative role in the repair of DNA damaged by bleomycin. The hypersensitivity of recA mutant to bleomycin and recAlexA-dependence of bleomycin-induced mutagenesis do not suggest any principal differences between UV-induced pyrimidine dimers and apyrimidinic sites in the case of post-replication repair. |
| المشرفين على المادة: | 0 (Bacterial Proteins) 0 (DNA, Bacterial) 11056-06-7 (Bleomycin) |
| تواريخ الأحداث: | Date Created: 19800101 Date Completed: 19810421 Latest Revision: 20201209 |
| رمز التحديث: | 20221213 |
| PMID: | 6161859 |
| قاعدة البيانات: | MEDLINE |
| تدمد: | 0016-6758 |
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