دورية أكاديمية
Hereditary abnormalities of thyroxine-binding globulin concentration. A study of 19 kindreds with inherited increase or decrease of thyroxine-binding globulin.
| العنوان: | Hereditary abnormalities of thyroxine-binding globulin concentration. A study of 19 kindreds with inherited increase or decrease of thyroxine-binding globulin. |
|---|---|
| المؤلفون: | Burr WA, Ramsden DB, Hoffenberg R |
| المصدر: | The Quarterly journal of medicine [Q J Med] 1980; Vol. 49 (195), pp. 295-313. |
| نوع المنشور: | Case Reports; Journal Article; Research Support, Non-U.S. Gov't |
| اللغة: | English |
| بيانات الدورية: | Publisher: Oxford University Press Country of Publication: England NLM ID: 0401027 Publication Model: Print Cited Medium: Print ISSN: 0033-5622 (Print) Linking ISSN: 00335622 NLM ISO Abbreviation: Q J Med Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: Oxford : Oxford University Press Original Publication: Oxford. |
| مواضيع طبية MeSH: | Alpha-Globulins/*analysis , Blood Protein Disorders/*genetics , Thyroxine-Binding Proteins/*analysis, Adult ; Blood Protein Disorders/blood ; Blood Protein Disorders/complications ; Child ; Female ; Humans ; Hyperthyroidism/complications ; Infant ; Male ; Middle Aged ; Myxedema/complications ; Pedigree ; Thyroxine/blood ; Thyroxine-Binding Proteins/deficiency ; Triiodothyronine/blood |
| مستخلص: | Nineteen families with hereditary abnormalities of thyroxine-binding globulin (TBG) have been studied, comprising a total of 15 males with absent TBG, and 15 females heterozygotic for this condition, and 14 males with excess of TBG and 44 heterozygotic females. Hereditary TBG excess was associated with thyrotoxicosis in four instances, and with myxoedema in three. The typical biochemical features of TBG abnormality are described, with the clinical histories of patients in whom diagnostic and management problems occurred. |
| المشرفين على المادة: | 0 (Alpha-Globulins) 0 (Thyroxine-Binding Proteins) 06LU7C9H1V (Triiodothyronine) Q51BO43MG4 (Thyroxine) |
| تواريخ الأحداث: | Date Created: 19800101 Date Completed: 19810424 Latest Revision: 20131121 |
| رمز التحديث: | 20221213 |
| PMID: | 6162169 |
| قاعدة البيانات: | MEDLINE |
| تدمد: | 0033-5622 |
|---|