دورية أكاديمية
Drug absorption VIII: Kinetics of GI absorption of methotrexate.
| العنوان: | Drug absorption VIII: Kinetics of GI absorption of methotrexate. |
|---|---|
| المؤلفون: | Chungi VS, Bourne DW, Dittert LW |
| المصدر: | Journal of pharmaceutical sciences [J Pharm Sci] 1978 Apr; Vol. 67 (4), pp. 560-1. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Elsevier Country of Publication: United States NLM ID: 2985195R Publication Model: Print Cited Medium: Print ISSN: 0022-3549 (Print) Linking ISSN: 00223549 NLM ISO Abbreviation: J Pharm Sci Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: 2016- : New York, NY : Elsevier Original Publication: Easton, Pa., American Pharmaceutical Assn. |
| مواضيع طبية MeSH: | Intestinal Absorption*, Methotrexate/*metabolism, Animals ; Kinetics ; Male ; Osmolar Concentration ; Rats |
| مستخلص: | The absorption of methotrexate from the lumen of the rat small intestine, in situ, was found to obey Michaelis--Menten kinetics. The values of Vmax and Km for the absorption process were 4.78 X 10(-7) M/min and 1.49 X 10(-5) M, respectively. |
| المشرفين على المادة: | YL5FZ2Y5U1 (Methotrexate) |
| تواريخ الأحداث: | Date Created: 19780401 Date Completed: 19780612 Latest Revision: 20190710 |
| رمز التحديث: | 20240627 |
| DOI: | 10.1002/jps.2600670434 |
| PMID: | 641772 |
| قاعدة البيانات: | MEDLINE |
| تدمد: | 0022-3549 |
|---|---|
| DOI: | 10.1002/jps.2600670434 |