دورية أكاديمية
أعرض في EDS

Serum amyloid A protein concentration in progressive systemic sclerosis (scleroderma).

التفاصيل البيبلوغرافية
العنوان: Serum amyloid A protein concentration in progressive systemic sclerosis (scleroderma).
المؤلفون: Brandwein SR, Medsger TA Jr, Skinner M, Sipe JD, Rodnan GP, Cohen AS
المصدر: Annals of the rheumatic diseases [Ann Rheum Dis] 1984 Aug; Vol. 43 (4), pp. 586-9.
نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
اللغة: English
بيانات الدورية: Publisher: BMJ Country of Publication: England NLM ID: 0372355 Publication Model: Print Cited Medium: Print ISSN: 0003-4967 (Print) Linking ISSN: 00034967 NLM ISO Abbreviation: Ann Rheum Dis Subsets: MEDLINE
أسماء مطبوعة: Publication: London : BMJ
Original Publication: London : H.K. Lewis
مواضيع طبية MeSH: Amyloid/*analysis , Scleroderma, Systemic/*blood , Serum Amyloid A Protein/*analysis, Amyloidosis/blood ; Amyloidosis/etiology ; Female ; Humans ; Male ; Scleroderma, Systemic/complications ; Scleroderma, Systemic/pathology
مستخلص: Serum amyloid A protein (SAA) concentrations were determined in 62 patients with progressive systemic sclerosis (PSS). Forty-seven patients had normal or slightly elevated SAA levels (less than 1000 ng/ml = micrograms/l), while 15 patients had moderately to markedly elevated SAA levels, similar to those observed in active rheumatoid arthritis (RA) (greater than or equal to 1000 ng/ml = micrograms/l). Five patients with PSS had SAA levels corresponding to those observed in amyloidosis secondary to RA. High SAA was associated with more severe skin thickening and diminished cumulative survival at five years. The rarity of amyloidosis secondary to PSS is unlikely to be related to an intrinsic defect in SAA production.
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معلومات مُعتمدة: AM 04599 United States AM NIADDK NIH HHS; AM 07014 United States AM NIADDK NIH HHS; AM 20613 United States AM NIADDK NIH HHS
المشرفين على المادة: 0 (Amyloid)
0 (Serum Amyloid A Protein)
تواريخ الأحداث: Date Created: 19840801 Date Completed: 19841002 Latest Revision: 20190503
رمز التحديث: 20231215
مُعرف محوري في PubMed: PMC1001414
DOI: 10.1136/ard.43.4.586
PMID: 6476917
قاعدة البيانات: MEDLINE
الوصف
تدمد:0003-4967
DOI:10.1136/ard.43.4.586