دورية أكاديمية
Effect of altered sterol composition on the osmotic behavior of sphaeroplasts and mitochondria of Saccharomyces cerevisiae.
العنوان: | Effect of altered sterol composition on the osmotic behavior of sphaeroplasts and mitochondria of Saccharomyces cerevisiae. |
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المؤلفون: | McLean-Bowen CA, Parks LW |
المصدر: | Lipids [Lipids] 1982 Sep; Vol. 17 (9), pp. 662-5. |
نوع المنشور: | Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S. |
اللغة: | English |
بيانات الدورية: | Publisher: Wiley Subscription Services, Inc Country of Publication: United States NLM ID: 0060450 Publication Model: Print Cited Medium: Print ISSN: 0024-4201 (Print) Linking ISSN: 00244201 NLM ISO Abbreviation: Lipids Subsets: MEDLINE |
أسماء مطبوعة: | Publication: 2018- : Hoboken, NJ : Wiley Subscription Services, Inc. Original Publication: Chicago, American Oil Chemists' Society. |
مواضيع طبية MeSH: | Saccharomyces cerevisiae/*physiology , Sterols/*analysis, Mitochondria/physiology ; Osmosis ; Saccharomyces cerevisiae/ultrastructure ; Spheroplasts/physiology |
مستخلص: | The effect of sterols on the osmotic stability of mitochondrial and plasma membranes of yeast wild-types and mutants that are defective in ergosterol biosynthesis has been studied. Incorporation of the nonfungal sterol, cholesterol, into yeast membranes reduces membrane elasticity which is observed as an increased susceptibility to osmotic lysis. However, the wild-type and nystatin-resistant strains which were examined indicate that qualitative alterations in endogenously generated sterols do not affect resistance to swelling. Although these strains exhibit differences in membrane fluidity, which is influenced by the sterol accumulated by the organisms, the membrane stretching capacity shows no distinct dependence on sterol structure or bilayer fluidity. |
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معلومات مُعتمدة: | AM-05190 United States AM NIADDK NIH HHS |
المشرفين على المادة: | 0 (Sterols) |
تواريخ الأحداث: | Date Created: 19820901 Date Completed: 19830119 Latest Revision: 20190814 |
رمز التحديث: | 20221213 |
DOI: | 10.1007/BF02535375 |
PMID: | 6755126 |
قاعدة البيانات: | MEDLINE |
تدمد: | 0024-4201 |
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DOI: | 10.1007/BF02535375 |