دورية أكاديمية
Chloroquine and quinine resistant Plasmodium falciparum on the island of Mindoro, Philippines, 1982.
| العنوان: | Chloroquine and quinine resistant Plasmodium falciparum on the island of Mindoro, Philippines, 1982. |
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| المؤلفون: | Smrkovski LL, Buck RL, Rodriguez CS, Wooster MT, Mayuga JL, Rivera D |
| المصدر: | The Southeast Asian journal of tropical medicine and public health [Southeast Asian J Trop Med Public Health] 1982 Dec; Vol. 13 (4), pp. 551-5. |
| نوع المنشور: | Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S. |
| اللغة: | English |
| بيانات الدورية: | Publisher: Central Coordinating Board for Tropical Medicine and public Health Project of SEAMEC Country of Publication: Thailand NLM ID: 0266303 Publication Model: Print Cited Medium: Print ISSN: 0125-1562 (Print) Linking ISSN: 01251562 NLM ISO Abbreviation: Southeast Asian J Trop Med Public Health Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: Bangkok, Thailand : Central Coordinating Board for Tropical Medicine and public Health Project of SEAMEC |
| مواضيع طبية MeSH: | Chloroquine/*pharmacology , Plasmodium falciparum/*drug effects , Quinine/*pharmacology, Drug Resistance ; Humans ; Philippines |
| مستخلص: | A field study was conducted on the island of Mindoro, Republic of the Philippines in which over 800 persons were screened for malaria and approximately 8% were found positive. The in vitro microtechnique was used to test for sensitivity to chloroquine, amodiaquine, mefloquine and quinine in 20 slide-confirmed P. falciparum cases. Sixteen of these cases were also followed for in vivo chloroquine sensitivity. Four cases showed in vitro resistance to chloroquine; 2 also showed resistance to quinine. All showed in vitro sensitivity to mefloquine and amodiaquine. The results of in vivo test were consistent with either a sensitive (S) or R-1, resistant response to chloroquine. Taken together, the in vitro and in vivo chloroquine tests indicate 4 cases of chloroquine resistance at the R1 level. |
| المشرفين على المادة: | 886U3H6UFF (Chloroquine) A7V27PHC7A (Quinine) |
| تواريخ الأحداث: | Date Created: 19821201 Date Completed: 19830623 Latest Revision: 20131121 |
| رمز التحديث: | 20240627 |
| PMID: | 6763355 |
| قاعدة البيانات: | MEDLINE |
| تدمد: | 0125-1562 |
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