دورية أكاديمية
Shock due to protamine hypersensitivity.
| العنوان: | Shock due to protamine hypersensitivity. |
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| المؤلفون: | Cobb CA 3rd, Fung DL |
| المصدر: | Surgical neurology [Surg Neurol] 1982 Apr; Vol. 17 (4), pp. 245-6. |
| نوع المنشور: | Case Reports; Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Elsevier Science Publishing Country of Publication: United States NLM ID: 0367070 Publication Model: Print Cited Medium: Print ISSN: 0090-3019 (Print) Linking ISSN: 00903019 NLM ISO Abbreviation: Surg Neurol Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: New York, NY : Elsevier Science Publishing Original Publication: Tryon, N. C., Bucy & Associates. |
| مواضيع طبية MeSH: | Protamines*, Drug Hypersensitivity/*complications , Shock/*etiology, Diabetes Mellitus/drug therapy ; Humans ; Insulin, Isophane/adverse effects ; Male ; Middle Aged |
| مستخلص: | A 56-year-old man developed shock and skin flush minutes after the slow administration of 25 mg of protamine sulfate. Prior protamine exposure from treatment of his diabetes with isophane insulin (NPH insulin) was believed to have sensitized this patient to protamine. A review of three other cases of reaction to low doses of protamine revealed that in each, the patient had previously been exposed to protamine. If heparin is used in a patient with a history of treatment of diabetes with isophane insulin, the heparin should be allowed to spontaneously reverse, without pharmacological assistance if possible. If protamine must be used, the patient should be pretreated with glucocorticoid and vasopressors should be immediately available. |
| المشرفين على المادة: | 0 (Protamines) 53027-39-7 (Insulin, Isophane) |
| تواريخ الأحداث: | Date Created: 19820401 Date Completed: 19820719 Latest Revision: 20190821 |
| رمز التحديث: | 20240627 |
| DOI: | 10.1016/0090-3019(82)90112-4 |
| PMID: | 7079946 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 0090-3019 |
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| DOI: | 10.1016/0090-3019(82)90112-4 |