دورية أكاديمية
Evaluation of Nd:YAG photocoagulation using a new experimental ulcer model with a single bleeding artery.
| العنوان: | Evaluation of Nd:YAG photocoagulation using a new experimental ulcer model with a single bleeding artery. |
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| المؤلفون: | Dennis MB, Silverstein FE, Gilbert DA, Peoples JE |
| المصدر: | Gastroenterology [Gastroenterology] 1981 Jun; Vol. 80 (6), pp. 1522-7. |
| نوع المنشور: | Journal Article; Research Support, U.S. Gov't, P.H.S. |
| اللغة: | English |
| بيانات الدورية: | Publisher: W.B. Saunders Country of Publication: United States NLM ID: 0374630 Publication Model: Print Cited Medium: Print ISSN: 0016-5085 (Print) Linking ISSN: 00165085 NLM ISO Abbreviation: Gastroenterology Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: Philadelphia, PA : W.B. Saunders Original Publication: Baltimore. |
| مواضيع طبية MeSH: | Laser Therapy*, Lasers/*instrumentation , Peptic Ulcer Hemorrhage/*surgery, Animals ; Arteries/surgery ; Disease Models, Animal ; Dogs ; Pilot Projects ; Stomach Ulcer/complications |
| مستخلص: | A new model of an acute bleeding gastric ulcer with a single bleeding artery in its base has been developed. A suction ulcer defect is created over a large, submucosal artery. Small bleeding marginal vessels are electrocoagulated with a fine-tipped bipolar forceps. The artery in the base of the ulcer is dissected free and then incised longitudinally; brisk bleeding results. A combination of heparin, aspirin, and dipyridamole is used to prevent spontaneous hemostasis. Bleeding from the incised artery of the single vessel ulcer does not decrease over a 10-min interval. No damage to the muscularis externa of the underlying gastric wall results from preparation of the ulcer. The effect of Nd:YAG laser photocoagulation in this new model was compared with the results of photocoagulation in the standard suction ulcer model. In both models the Nd:YAG laser stopped equivalent bleeding from all ulcers. However, there was a marked difference in the depth of tissue injury, with much less damage observed in the single vessel ulcer. This model may provide a better method to assess depth of tissue injury resulting from endoscopic hemostatic techniques. |
| معلومات مُعتمدة: | 1-P40-RR01203 United States RR NCRR NIH HHS; 1-R01-GM25262 United States GM NIGMS NIH HHS; N01-AM-5--2211 United States AM NIADDK NIH HHS |
| تواريخ الأحداث: | Date Created: 19810601 Date Completed: 19810709 Latest Revision: 20071115 |
| رمز التحديث: | 20221213 |
| PMID: | 7194830 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 0016-5085 |
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