دورية أكاديمية
Use of polyclonal IgG in HIV infection and AIDS.
| العنوان: | Use of polyclonal IgG in HIV infection and AIDS. |
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| المؤلفون: | Buscombe JR; Department of Nuclear Medicine, Royal Free Hospital, London, UK., Oyen WJ, Corstens FH |
| المصدر: | The quarterly journal of nuclear medicine : official publication of the Italian Association of Nuclear Medicine (AIMN) [and] the International Association of Radiopharmacology (IAR) [Q J Nucl Med] 1995 Sep; Vol. 39 (3), pp. 212-20. |
| نوع المنشور: | Journal Article; Review |
| اللغة: | English |
| بيانات الدورية: | Publisher: Minerva Medica Country of Publication: Italy NLM ID: 9512274 Publication Model: Print Cited Medium: Print ISSN: 1125-0135 (Print) Linking ISSN: 11250135 NLM ISO Abbreviation: Q J Nucl Med Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: Torino : Minerva Medica, c1995-c2003. |
| مواضيع طبية MeSH: | Immunoglobulin G* , Indium Radioisotopes* , Technetium*, AIDS-Related Opportunistic Infections/*diagnosis, Humans |
| مستخلص: | Nuclear Medicine should have a pivitol role to play in the investigation of patients infected with the human immunodeficiency virus (HIV). Unfortunately the use of scintigraphic techniques to localise infection have not become widely used in Europe. Neither 67Ga citrate or labelled leukocytes are ideal. In a search for new agents which can be used to identify the presence of infection both 99mTc and 111In labelled polyclonal immunoglobulin-C have been investigated. It was found that 99mTc labelled polyclonal immune-globulin-G was not able to localise infection in either the chest or the abdomen. In contrast 111In labelled polyclonal immunoglobulin-G had both high sensitivity and specificity for imaging infection in HIV infected patients. If these preliminary results are confirmed immunoglobulin-G could find an important clinical application in this specialised patient group. |
| Number of References: | 34 |
| المشرفين على المادة: | 0 (Immunoglobulin G) 0 (Indium Radioisotopes) 7440-26-8 (Technetium) |
| تواريخ الأحداث: | Date Created: 19950901 Date Completed: 19951122 Latest Revision: 20151119 |
| رمز التحديث: | 20221213 |
| PMID: | 7552944 |
| قاعدة البيانات: | MEDLINE |
| تدمد: | 1125-0135 |
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