دورية أكاديمية
Double-blind cross-over evaluation of mazindol in the treatment of obese hypertensive patients.
| العنوان: | Double-blind cross-over evaluation of mazindol in the treatment of obese hypertensive patients. |
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| المؤلفون: | Miach PJ, Thomson W, Doyle AE, Louis WJ |
| المصدر: | The Medical journal of Australia [Med J Aust] 1976 Sep 04; Vol. 2 (10), pp. 378-80. |
| نوع المنشور: | Clinical Trial; Controlled Clinical Trial; Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Australasian Medical Publishing Co Country of Publication: Australia NLM ID: 0400714 Publication Model: Print Cited Medium: Print ISSN: 0025-729X (Print) Linking ISSN: 0025729X NLM ISO Abbreviation: Med J Aust Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: Original Publication: Sydney : Australasian Medical Pub. Co. |
| مواضيع طبية MeSH: | Hypertension/*drug therapy , Indoles/*therapeutic use , Mazindol/*therapeutic use , Obesity/*drug therapy, Adult ; Aged ; Clinical Trials as Topic ; Female ; Humans ; Hypertension/complications ; Male ; Mazindol/adverse effects ; Middle Aged ; Obesity/complications ; Placebos |
| مستخلص: | The effect of mazindol (AN 448) on weight and blood pressure was evaluated in a double-blind cross-over trial in 28 obese hypertensive patients, whose blood pressure was under stable control with one or more of the common antihypertensive agents--diuretics, beta-blocking drugs and methyldopa. There was a statistically significant decrease in weight, but no significant change in blood pressure (systolic and diastolic) or pulse rate during active treatment. It was considered that the drug might be of benefit to some patients, provided that they were properly motivated to adhere to the dietary regime. |
| المشرفين على المادة: | 0 (Indoles) 0 (Placebos) C56709M5NH (Mazindol) |
| تواريخ الأحداث: | Date Created: 19760904 Date Completed: 19770125 Latest Revision: 20210313 |
| رمز التحديث: | 20240513 |
| DOI: | 10.5694/j.1326-5377.1976.tb130259.x |
| PMID: | 792640 |
| قاعدة البيانات: | MEDLINE |
| تدمد: | 0025-729X |
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| DOI: | 10.5694/j.1326-5377.1976.tb130259.x |