دورية أكاديمية
2-deoxyglucose-induced food intake by Nile tilapia, Oreochromis niloticus (L.).
| العنوان: | 2-deoxyglucose-induced food intake by Nile tilapia, Oreochromis niloticus (L.). |
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| المؤلفون: | Delicio HC; Departamento de Fisiologia, Universidade Estadual Paulista, Júlio de Mesquita Filho, Botucatu, SP, Brasil., Vicentini-Paulino ML |
| المصدر: | Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas [Braz J Med Biol Res] 1993 Mar; Vol. 26 (3), pp. 327-31. |
| نوع المنشور: | Journal Article; Research Support, Non-U.S. Gov't |
| اللغة: | English |
| بيانات الدورية: | Publisher: Associação Brasileira de Divulgação Científica Country of Publication: Brazil NLM ID: 8112917 Publication Model: Print Cited Medium: Print ISSN: 0100-879X (Print) Linking ISSN: 0100879X NLM ISO Abbreviation: Braz J Med Biol Res Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: [SP, Brasil : Associação Brasileira de Divulgação Científica, 1981- |
| مواضيع طبية MeSH: | Blood Glucose/*analysis , Deoxyglucose/*pharmacology , Feeding Behavior/*drug effects , Fishes/*physiology, Animals ; Fishes/blood |
| مستخلص: | The alimentary and glycemic responses to cytoglycopenia were studied in thirty-one Nile tilapia alevins of indeterminate sex and age, measuring on average 10.67 +/- 0.82 cm. The cytoglycopenia was provoked by ip injection of 60 mg/kg 2-deoxy-D-glucose (2-DG, N = 16). The control group (N = 15) was submitted to ip injection of 0.2 ml saline. Blood samples for glucose determination were obtained before and three hours after drug administration by cardiac puncture. Food was then offered ad libitum. One hour later the animals were sacrificed and their stomachs removed. The difference in wet weight between full and empty stomach was utilized to quantify the food intake. Median food intake was 0.3877 g for the fish treated with 2-DG and 0.107 g for the animals injected with saline. This difference was statistically significant by the Mann-Whitney test (P < 0.05). The median values of blood glucose levels before drug injection were 46.19 mg/100 ml in the 2-DG-treated fish and 44.54 mg/100 ml in the control group. Three hours after drug administration, the values were 48.64 mg/100 ml in the experimental group and 56.90 mg/100 ml in the control group. The difference between the values of blood glucose before and after the drug was not significant for either group. We conclude that glucoprivation provokes food intake in fish and that the same glucoprivation was not sufficient to provoke hyperglycemia. |
| المشرفين على المادة: | 0 (Blood Glucose) 9G2MP84A8W (Deoxyglucose) |
| تواريخ الأحداث: | Date Created: 19930301 Date Completed: 19940119 Latest Revision: 20161018 |
| رمز التحديث: | 20240627 |
| PMID: | 8257932 |
| قاعدة البيانات: | MEDLINE |
| تدمد: | 0100-879X |
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