دورية أكاديمية
Progressive visual deterioration leading to blindness after pediatric heart transplantation.
| العنوان: | Progressive visual deterioration leading to blindness after pediatric heart transplantation. |
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| المؤلفون: | Schowengerdt KO Jr; Division of Pediatric Cardiology, Texas Children's Hospital, Houston 77030., Gajarski RJ, Denfield S |
| المصدر: | Texas Heart Institute journal [Tex Heart Inst J] 1993; Vol. 20 (4), pp. 299-303. |
| نوع المنشور: | Case Reports; Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: published in the Cardiovascular Surgical Research Laboratories, Texas Heart Institute Country of Publication: United States NLM ID: 8214622 Publication Model: Print Cited Medium: Print ISSN: 0730-2347 (Print) Linking ISSN: 07302347 NLM ISO Abbreviation: Tex Heart Inst J Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: Houston, TX : published in the Cardiovascular Surgical Research Laboratories, Texas Heart Institute, c1982- |
| مواضيع طبية MeSH: | Blindness/*etiology , Heart Transplantation/*adverse effects , Immunosuppressive Agents/*adverse effects , Pseudotumor Cerebri/*etiology, Child ; Female ; Graft Rejection ; Humans ; Pseudotumor Cerebri/complications ; Time Factors |
| مستخلص: | We present the case of a 10-year-old girl who developed visual loss progressing to blindness after orthotopic heart transplantation and an immunosuppressive regimen of cyclosporine, azathioprine, and prednisone. Headaches and visual deterioration began 2 months after transplantation, and a diagnosis of pseudotumor cerebri was made. The patient's visual loss continued despite aggressive medical and surgical therapy, which included bilateral optic nerve sheath fenestration. To our knowledge, permanent visual loss as a late sequela following pediatric heart transplantation and immunosuppressive therapy has not been reported previously in the English literature. Although the cause of visual loss after transplantation in our patient is poorly understood, we conclude that permanent visual loss, although rare, should be considered as a possible late neurologic sequela after pediatric heart transplantation. |
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| المشرفين على المادة: | 0 (Immunosuppressive Agents) |
| تواريخ الأحداث: | Date Created: 19930101 Date Completed: 19940310 Latest Revision: 20181113 |
| رمز التحديث: | 20240627 |
| مُعرف محوري في PubMed: | PMC325116 |
| PMID: | 8298330 |
| قاعدة البيانات: | MEDLINE |
| تدمد: | 0730-2347 |
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