دورية أكاديمية
Endomyocardial fibrosis and eosinophilia.
العنوان: | Endomyocardial fibrosis and eosinophilia. |
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المؤلفون: | Patel AK, D'Arbela PG, Somers K |
المصدر: | British heart journal [Br Heart J] 1977 Mar; Vol. 39 (3), pp. 238-41. |
نوع المنشور: | Journal Article |
اللغة: | English |
بيانات الدورية: | Publisher: BMJ Pub. Group [etc.] Country of Publication: England NLM ID: 0370634 Publication Model: Print Cited Medium: Print ISSN: 0007-0769 (Print) Linking ISSN: 00070769 NLM ISO Abbreviation: Br Heart J Subsets: MEDLINE |
أسماء مطبوعة: | Original Publication: London, BMJ Pub. Group [etc.] |
مواضيع طبية MeSH: | Endomyocardial Fibrosis/*complications , Eosinophilia/*complications, Adolescent ; Adult ; Child ; Endomyocardial Fibrosis/blood ; Endomyocardial Fibrosis/parasitology ; Eosinophils ; Female ; Humans ; Leukocyte Count ; Liver/pathology ; Male ; Uganda |
مستخلص: | Absolute eosinophil counts were assessed in 15 African patients with proven endomyocardial fibrosis. Though the mean eosinophil count in patients with endomyocardial fibrosis was higher compared with the normals reported from Kampala (1-13 vs 0.72X10(9)/1), the absolute range was comparable. A high percentage of patients with endomyocardial fibrosis had malarial parasites, high malarial antibody titres, hookworms, or strongyloides, but the correlation of eosinophilia to various parasitic infections was poor. Both eosinophilia and parasitic infections are common in the tropics and they effect patients with endomyocardial fibrosis no more than the population at large. Other aetiological factors, genetic, environmental, and immunological, are felt to be important in the causation of endomyocardial fibrosis in Uganda and evidence for this is reviewed. Though there is a similarity in pathological features, African endomyocardial fibrosis is a distinct entity from Löffler's endocarditis and cardiac lesions seen in eosinophilic leukaemia or reactive eosinophilia. There is no hard evidence to suggest that African endomyocardial fibrosis is a variant of Löffler's endocarditis caused by parasitic infections via eosinophilia. |
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تواريخ الأحداث: | Date Created: 19770301 Date Completed: 19770527 Latest Revision: 20190503 |
رمز التحديث: | 20231215 |
مُعرف محوري في PubMed: | PMC483227 |
DOI: | 10.1136/hrt.39.3.238 |
PMID: | 849383 |
قاعدة البيانات: | MEDLINE |
تدمد: | 0007-0769 |
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DOI: | 10.1136/hrt.39.3.238 |