دورية أكاديمية
Compound motor action potential recording distinguishes differential onset of motor block of the obturator nerve in response to etidocaine or bupivacaine.
| العنوان: | Compound motor action potential recording distinguishes differential onset of motor block of the obturator nerve in response to etidocaine or bupivacaine. |
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| المؤلفون: | Atanassoff PG; Department of Anesthesiology, Yale University School of Medicine, New Haven, Connecticut 06510, USA., Weiss BM, Brull SJ, Horst A, Külling D, Stein R, Theiler I |
| المصدر: | Anesthesia and analgesia [Anesth Analg] 1996 Feb; Vol. 82 (2), pp. 317-20. |
| نوع المنشور: | Clinical Trial; Comparative Study; Journal Article; Randomized Controlled Trial |
| اللغة: | English |
| بيانات الدورية: | Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 1310650 Publication Model: Print Cited Medium: Print ISSN: 0003-2999 (Print) Linking ISSN: 00032999 NLM ISO Abbreviation: Anesth Analg Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: 1998- : Baltimore, Md. : Lippincott Williams & Wilkins Original Publication: Cleveland, International Anesthesia Research Society. |
| مواضيع طبية MeSH: | Evoked Potentials, Motor* , Nerve Block*, Anesthetics, Local/*administration & dosage , Bupivacaine/*administration & dosage , Etidocaine/*administration & dosage , Leg/*innervation, Adult ; Anesthesia, Spinal ; Anesthetics, Local/pharmacology ; Bupivacaine/pharmacology ; Etidocaine/pharmacology ; Female ; Humans ; Male ; Neural Conduction/drug effects |
| مستخلص: | The purpose of this investigation was to establish an objective (quantitative) method for determining onset time of motor block induced by different local anesthetics. Twenty-four consenting patients undergoing transurethral surgery during spinal anesthesia were randomized to receive direct obturator nerve block with 10 mL of plain bupivacaine 0.5% (n = 12) or 10 mL of plain etidocaine 1% (n = 12). Another 14 patients (control group) received obturator nerve "block" with saline. After identification of the obturator nerve, patients underwent testing of nerve conduction by recording compound motor action potentials (CMAPs) of thigh adductor muscles in response to stimulation provided by a nerve stimulator at 0.2 to 0.5-mA currents. Testing ended when CMAP amplitudes had returned to their baseline values (control group) or when motor blockade was 90% complete (local anesthetic groups). In all 38 patients, the amplitude of the thigh CMAPs decreased immediately after injection of saline or local anesthetic. While CMAP amplitudes in the control group returned to their initial (baseline) values after 3-6 min, the patients receiving etidocaine or bupivacaine achieved > or = 90% motor blockade after 6 and 13 min, respectively. In the present report, the time to > or = 90% block was significantly faster in patients given etidocaine compared with those given bupivacaine. We conclude that electromyographic recording of CMAPs can be used to compare the ability of different local anesthetics to induce motor block. |
| المشرفين على المادة: | 0 (Anesthetics, Local) I6CQM0F31V (Etidocaine) Y8335394RO (Bupivacaine) |
| تواريخ الأحداث: | Date Created: 19960201 Date Completed: 19960228 Latest Revision: 20220311 |
| رمز التحديث: | 20221213 |
| DOI: | 10.1097/00000539-199602000-00018 |
| PMID: | 8561334 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 0003-2999 |
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| DOI: | 10.1097/00000539-199602000-00018 |