دورية أكاديمية
Primary gastric lymphoma: a 15-year review.
| العنوان: | Primary gastric lymphoma: a 15-year review. |
|---|---|
| المؤلفون: | Speranza V; Cattedra di Clinica Chirurgica II, University of Rome La Sapienza, Italy., Lomanto D, Meli EZ, Basoli A, Carlei F, Ligydakis NJ, Lezoche E |
| المصدر: | Hepato-gastroenterology [Hepatogastroenterology] 1995 Jul-Aug; Vol. 42 (4), pp. 371-6. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Thieme Country of Publication: Greece NLM ID: 8007849 Publication Model: Print Cited Medium: Print ISSN: 0172-6390 (Print) Linking ISSN: 01726390 NLM ISO Abbreviation: Hepatogastroenterology Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: Stuttgart, Thieme. |
| مواضيع طبية MeSH: | Lymphoma, Non-Hodgkin/*surgery , Stomach Neoplasms/*surgery, Adult ; Female ; Humans ; Lymphoma, Non-Hodgkin/diagnosis ; Lymphoma, Non-Hodgkin/mortality ; Male ; Middle Aged ; Prognosis ; Retrospective Studies ; Sensitivity and Specificity ; Stomach Neoplasms/diagnosis ; Stomach Neoplasms/mortality ; Survival Rate |
| مستخلص: | Background/aim: Between 1976 and 1991, 25 patients underwent surgical therapy for primary gastric lymphoma. Clinical records were reviewed retrospectively to evaluate prognostic factors and impact of treatment on survival. Results: Diagnostic sensitivity of endoscopic biopsy was 68%, positively of barium contrast studies for tumor was 33%. The overall 5-year survival rate was 67.3% (51.7% "free disease"): it was for stage I E 88.9%, for stages II 1E and II 2E respectively 68.6% and 44.4% and for stage IV 33.4%. Patients with tumors smaller than 5 cm had a 5-year survival rate of 80.8% whereas for patients with larger lesions survival rate was 44% (p < 0.05). Patients with low grade malignancy tumors had a 5-year survival rate of 81.9% versus 37.5% for high grade malignancy tumors (p < 0.03). Chemotherapy as adjuvant therapy was used in 17 cases (68%). 53% of them are "free disease" at minimum 4 years from the operation. Conclusions: We conclude that, surgical management of primary gastric lymphoma is mandatory but a planned multimodality therapy may produce complete remission and long-term "free disease" survival rate even in patients with relapse. |
| تواريخ الأحداث: | Date Created: 19950701 Date Completed: 19960327 Latest Revision: 20041117 |
| رمز التحديث: | 20231215 |
| PMID: | 8586371 |
| قاعدة البيانات: | MEDLINE |
| تدمد: | 0172-6390 |
|---|