دورية أكاديمية
Interleukin (IL)-6 and IL-8 in children with febrile urinary tract infection and asymptomatic bacteriuria.
| العنوان: | Interleukin (IL)-6 and IL-8 in children with febrile urinary tract infection and asymptomatic bacteriuria. |
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| المؤلفون: | Benson M; Department of Pediatrics, East Hospital, Göteborg, Sweden., Jodal U, Agace W, Hellström M, Mårild S, Rosberg S, Sjöström M, Wettergren B, Jönsson S, Svanborg C |
| المصدر: | The Journal of infectious diseases [J Infect Dis] 1996 Nov; Vol. 174 (5), pp. 1080-4. |
| نوع المنشور: | Journal Article; Research Support, Non-U.S. Gov't |
| اللغة: | English |
| بيانات الدورية: | Publisher: Oxford University Press Country of Publication: United States NLM ID: 0413675 Publication Model: Print Cited Medium: Print ISSN: 0022-1899 (Print) Linking ISSN: 00221899 NLM ISO Abbreviation: J Infect Dis Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: Jan. 2011- : Oxford : Oxford University Press Original Publication: 1904-2010 : Chicago, IL : University of Chicago Press |
| مواضيع طبية MeSH: | Bacteriuria/*metabolism , Fever/*metabolism , Interleukin-6/*analysis , Interleukin-8/*analysis , Urinary Tract Infections/*metabolism, Child, Preschool ; Female ; Fimbriae, Bacterial/physiology ; Humans ; Infant ; Male ; Sex Factors |
| مستخلص: | Urine and serum interleukin (IL)-6 and IL-8 responses were higher in children with febrile urinary tract infection (n = 61) than in those with asymptomatic bacteriuria (n = 39). By univariate analysis, cytokine levels were related to age, sex, reflux, renal scarring, urine leukocytes, C-reactive protein (CRP), erythrocyte sedimentation rate (ESR), and bacterial properties (P fimbriae but not hemolysin). Multivariate modeling showed that urine IL-6 responses were higher in girls than boys, increased with age, and were positively associated with CRP, ESR, serum IL-6, and urine leukocyte counts. The urine IL-8 response was not influenced by age, but it was influenced by P fimbriae and was associated with ESR, CRP, urine leukocytes, and female sex. The results show that cytokine responses to urinary tract infection vary with the severity of infection and that cytokine activation is influenced by a variety of host and bacterial variables. |
| المشرفين على المادة: | 0 (Interleukin-6) 0 (Interleukin-8) |
| تواريخ الأحداث: | Date Created: 19961101 Date Completed: 19961127 Latest Revision: 20190512 |
| رمز التحديث: | 20231215 |
| DOI: | 10.1093/infdis/174.5.1080 |
| PMID: | 8896512 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 0022-1899 |
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| DOI: | 10.1093/infdis/174.5.1080 |