دورية أكاديمية
Direct cortico-motoneuronal synaptic contacts are present in the adult rat cervical spinal cord and are first established at postnatal day 7.
| العنوان: | Direct cortico-motoneuronal synaptic contacts are present in the adult rat cervical spinal cord and are first established at postnatal day 7. |
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| المؤلفون: | Curfs MH; Department of Anatomy and Embryology, Faculty of Medical Sciences, University of Nijmegen, The Netherlands., Gribnau AA, Dederen PJ |
| المصدر: | Neuroscience letters [Neurosci Lett] 1996 Feb 23; Vol. 205 (2), pp. 123-6. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Elsevier Scientific Publishers Ireland Country of Publication: Ireland NLM ID: 7600130 Publication Model: Print Cited Medium: Print ISSN: 0304-3940 (Print) Linking ISSN: 03043940 NLM ISO Abbreviation: Neurosci Lett Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: Limerick : Elsevier Scientific Publishers Ireland Original Publication: Amsterdam, Elsevier/North-Holland. |
| مواضيع طبية MeSH: | Motor Neurons/*cytology , Pyramidal Tracts/*cytology , Synapses/*ultrastructure, Afferent Pathways ; Age Factors ; Animals ; Animals, Newborn ; Cerebral Cortex/cytology ; Female ; Horseradish Peroxidase ; Male ; Microscopy, Electron ; Motor Neurons/ultrastructure ; Neural Pathways ; Pyramidal Tracts/growth & development ; Rats ; Rats, Wistar ; Spinal Cord/cytology ; Time Factors |
| مستخلص: | In order to demonstrate direct cortico-motoneuronal synaptic contacts in the cervical spinal cord of the rat and to determine at which postnatal age these contacts are established, an electron microscopic study using double labelling was performed. Corticospinal axons were anterogradely labelled after horseradish peroxidase (HRP)-gel implantation into the cerebral motor cortex and motoneurons were retrogradely labelled after cholera toxin subunit B conjugated to HRP (CTB-HRP) injections into the distal forelimb flexor muscle. With the histochemical procedures used, both tracers yield similar needle-like crystalline deposits. Labelled axons, however, can be well differentiated from labelled motoneuronal dendrites and somata on morphological grounds. In adult rats, direct cortico-motoneuronal contacts were encountered. Experiments in developing postnatal rats demonstrated that these synapses are first present on postnatal day 7. |
| المشرفين على المادة: | EC 1.11.1.- (Horseradish Peroxidase) |
| تواريخ الأحداث: | Date Created: 19960223 Date Completed: 19970307 Latest Revision: 20190701 |
| رمز التحديث: | 20231215 |
| DOI: | 10.1016/0304-3940(96)12396-x |
| PMID: | 8907332 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 0304-3940 |
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| DOI: | 10.1016/0304-3940(96)12396-x |