التفاصيل البيبلوغرافية
| العنوان: |
[Cloning proviral DNA sequences of the human T-cell leukemia virus (HTLV-1) from the genome of cultured MT-4 cells]. |
| عنوان ترانسليتريتد: |
Klornirovanie provirusnykh DNK-posledovatel'nosteĭ virusa T-kletochnogo leĭkoza cheloveka tipa 1 (HTLV-1) iz genoma kul'tury kletok MT-4. |
| المؤلفون: |
Susloparov MA, Krendel'shchikov AV, Bakhtina MM, Bedristov AI, Babkin IV, Gutorov VV, Eroshkin AM, Mamaeva OA |
| المصدر: |
Molekuliarnaia genetika, mikrobiologiia i virusologiia [Mol Gen Mikrobiol Virusol] 1996 Apr-Jun (2), pp. 32-9. |
| نوع المنشور: |
English Abstract; Journal Article |
| اللغة: |
Russian |
| بيانات الدورية: |
Publisher: Meditsina Country of Publication: Russia (Federation) NLM ID: 9315607 Publication Model: Print Cited Medium: Print ISSN: 0208-0613 (Print) Linking ISSN: 02080613 NLM ISO Abbreviation: Mol Gen Mikrobiol Virusol Subsets: MEDLINE |
| أسماء مطبوعة: |
Original Publication: Moskva : Meditsina, |
| مواضيع طبية MeSH: |
Human T-lymphotropic virus 1/*genetics , Proviruses/*genetics, Amino Acid Sequence ; Bacteria/genetics ; Base Sequence ; Cell Line ; DNA, Recombinant ; Genes, env ; Humans ; Molecular Sequence Data ; Point Mutation |
| مستخلص: |
MT-4 cell line is a continuous strain of human T lymphocytes expressing defective noninfective subviral HTLV-1 particles. A fragment of sequence encoding the p24 protein and gene for envelope protein (env) have been obtained from genomic DNA of this culture by polymerase chain reaction. Both HTLV-1 fragments were cloned in bacterial vectors, and the nucleotide sequence of these regions was determined. The cloned DNA fragment encoding the p24 has only four point nucleotide exchanges. Analysis of the env gene structure revealed that the sequence had several amino acid exchanges and two deletions (13 bp and 70 bp). |
| المشرفين على المادة: |
0 (DNA, Recombinant) |
| تواريخ الأحداث: |
Date Created: 19960401 Date Completed: 19961127 Latest Revision: 20061115 |
| رمز التحديث: |
20240627 |
| PMID: |
8927062 |
| قاعدة البيانات: |
MEDLINE |
