دورية أكاديمية
[Pseudoallergic reactions. Intolerance to natural and synthetic food constituents masquerading as food allergy].
| العنوان: | [Pseudoallergic reactions. Intolerance to natural and synthetic food constituents masquerading as food allergy]. |
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| عنوان ترانسليتريتد: | Pokarmowe reakcje pseudoalergiczne (PAR): nietolerancje naturalnych i syntetycznych składników pozywienia naśladujace objawy alergii. |
| المؤلفون: | Kurek M; Klinika Gastroenterologii Instytutu Chorób Wewnetiznych Akademii Medycznej w Gdansku. |
| المصدر: | Pediatria polska [Pediatr Pol] 1996 Sep; Vol. 71 (9), pp. 743-52. |
| نوع المنشور: | English Abstract; Journal Article; Review |
| اللغة: | Polish |
| بيانات الدورية: | Publisher: Elsevier Urban & Partner Country of Publication: Poland NLM ID: 2985039R Publication Model: Print Cited Medium: Print ISSN: 0031-3939 (Print) Linking ISSN: 00313939 NLM ISO Abbreviation: Pediatr Pol Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: 2006- : Wrocław : Elsevier Urban & Partner Original Publication: Warszawa : Urban And Partner Wydawnictwo Medyczne |
| مواضيع طبية MeSH: | Food Hypersensitivity/*etiology, Diagnosis, Differential ; Food Hypersensitivity/diagnosis ; Food Hypersensitivity/prevention & control ; Humans ; Receptors, Histamine H1/physiology ; Skin Tests |
| مستخلص: | Adverse hypersensitivity reactions to natural foods and certain drugs and food additives are mediated by immunological (allergy) or non-immunological mechanisms. Some clinical and physiological similarities have been noted between these allergic and non-allergic reactions. This observation has led to the concept of "pseudoallergic reactions-PAR". PAR can be triggered in various ways such as: interactions with the central or peripherical nervous system, non-specific release of mediators, enzyme inhibition due to hereditary or pharmacologically induced enzyme deficiencies and pharmacological properties of some natural food constituents such as biogenic amines. The prevalence of adverse reactions to food additives has been calculated to be about 0.1%. PAR to food additives occurs frequently in patients suffering from urticaria, asthma and may be accompanied by history of aspirin or NSAI pseudoallergic reactions. The same additives (azo dyes, sulphites, benzoates) are used in various drug formulations and may be responsible for eliciting PAR. In Poland, labelling of food additives, following the "E number system", has been mandatory since 1993. Unfortunately, this satisfactory trend has not yet been applied to drug additives. The diagnosis of PAR to food additives is based on the anamnesis with analysis of the patient's drug and dietary intake. Skin tests and "in vitro" tests are only sporadically informative. In each individual patient, a specific challenge with additives is desirable. Food additives may be tested according to the schedule based on DBPCFC principle. Individually performed exclusion regimes are the principal methods of prevention. |
| Number of References: | 37 |
| المشرفين على المادة: | 0 (Receptors, Histamine H1) |
| تواريخ الأحداث: | Date Created: 19960901 Date Completed: 19961122 Latest Revision: 20061115 |
| رمز التحديث: | 20221213 |
| PMID: | 8927481 |
| قاعدة البيانات: | MEDLINE |
| تدمد: | 0031-3939 |
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