دورية أكاديمية
[D-penicillamine in treatment of scleroderma "en coup de sabre"].
| العنوان: | [D-penicillamine in treatment of scleroderma "en coup de sabre"]. |
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| عنوان ترانسليتريتد: | D-Penizillamin in der Behandlung von Sklerodermie "en coup de sabre". |
| المؤلفون: | van Bergen BH; Universitätsklinik für Hautkrankheiten, Katholische Universität, Nijmegen., van Dooren-Greebe RJ, Fiselier TJ, Koopman RJ |
| المصدر: | Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete [Hautarzt] 1997 Jan; Vol. 48 (1), pp. 42-4. |
| نوع المنشور: | Case Reports; English Abstract; Journal Article |
| اللغة: | German |
| بيانات الدورية: | Publisher: Springer Verlag Country of Publication: Germany NLM ID: 0372755 Publication Model: Print Cited Medium: Print ISSN: 0017-8470 (Print) Linking ISSN: 00178470 NLM ISO Abbreviation: Hautarzt Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: Berlin : Springer Verlag |
| مواضيع طبية MeSH: | Antirheumatic Agents/*administration & dosage , Penicillamine/*administration & dosage , Scleroderma, Localized/*drug therapy, Adolescent ; Follow-Up Studies ; Forehead ; Humans ; Male ; Scleroderma, Localized/diagnosis |
| مستخلص: | A ten year old boy with linear erythema above the right eyebrow and a groove in the underlying skull bone is described. Histological examination of a biopsy revealed a spotty, periadnexal, perivascular, lymphocytic infiltrate. The papillary dermis was almost absent and the collagen fibres were slightly thickened. Based on the clinical appearance and the histology a diagnosis of linear scleroderma (en coup de sabre) was made. As the signs and symptoms were progressive, treatment with D-penicillamine was started. Subsequently the erythema disappeared. The shallow groove in the skull bone remained palpable. After thirteen months, treatment was stopped. The patient is currently free of signs and symptoms after a follow-up period of three and a half years. We feel that the strong clinical improvement is due to treatment with D-penicillamine rather than to the natural course of the disease. |
| المشرفين على المادة: | 0 (Antirheumatic Agents) GNN1DV99GX (Penicillamine) |
| تواريخ الأحداث: | Date Created: 19970101 Date Completed: 19970430 Latest Revision: 20190920 |
| رمز التحديث: | 20231215 |
| DOI: | 10.1007/s001050050545 |
| PMID: | 9132387 |
| قاعدة البيانات: | MEDLINE |
Find this article in full text from Springer Verlag. 
Full Text Finder | تدمد: | 0017-8470 |
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| DOI: | 10.1007/s001050050545 |