التفاصيل البيبلوغرافية
| العنوان: |
A developmental model for studying choline acetyltransferase transport in chick motoneurons. |
| المؤلفون: |
Giacobini G, Cannas M, Panattoni GL, Filogamo G |
| المصدر: |
Developmental neuroscience [Dev Neurosci] 1979; Vol. 2 (5), pp. 225-34. |
| نوع المنشور: |
Journal Article |
| اللغة: |
English |
| بيانات الدورية: |
Publisher: Karger Country of Publication: Switzerland NLM ID: 7809375 Publication Model: Print Cited Medium: Print ISSN: 0378-5866 (Print) Linking ISSN: 03785866 NLM ISO Abbreviation: Dev Neurosci Subsets: MEDLINE |
| أسماء مطبوعة: |
Original Publication: Basel, New York, Karger. |
| مواضيع طبية MeSH: |
Aging* , Axonal Transport*, Choline O-Acetyltransferase/*metabolism , Motor Neurons/*enzymology , Sciatic Nerve/*enzymology, Animals ; Chickens ; Spinal Cord/enzymology |
| مستخلص: |
The proximodistal axonal transport of choline acetyltransferase (ChAc) has been studied in the chick sciatic nerve in the absence of any experimental manipulation. The phenomenon utilized by us is a physiological transient fall in the activity of ChAc. This fall occurs in most areas of the chick central nervous system after hatching, and moves toward the periphery along the nerves. Having ruled out the presence of transient inhibitors, the movement of the fall towards skeletal muscles has been considered to correspond to the proximodistal transport of ChAc. The calculated average velocity is 7.86 mm/day, corresponding to the slow rate of transport. Nevertheless, the kinematics study suggests that the velocity varies along the nerve from a state of rest to an intermediate rate of transport (16 mm/day). The possible influence of variations in the resistance of the conductor on these changes in velocity is discussed. |
| المشرفين على المادة: |
EC 2.3.1.6 (Choline O-Acetyltransferase) |
| تواريخ الأحداث: |
Date Created: 19790101 Date Completed: 19800514 Latest Revision: 20180214 |
| رمز التحديث: |
20231215 |
| DOI: |
10.1159/000112484 |
| PMID: |
94010 |
| قاعدة البيانات: |
MEDLINE |
