دورية أكاديمية
Purpura fulminans in pneumococcal sepsis: case report and review.
| العنوان: | Purpura fulminans in pneumococcal sepsis: case report and review. |
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| المؤلفون: | Carpenter CT; Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN, USA., Kaiser AB |
| المصدر: | Scandinavian journal of infectious diseases [Scand J Infect Dis] 1997; Vol. 29 (5), pp. 479-83. |
| نوع المنشور: | Case Reports; Journal Article; Review |
| اللغة: | English |
| بيانات الدورية: | Publisher: Informa Healthcare Country of Publication: England NLM ID: 0215333 Publication Model: Print Cited Medium: Print ISSN: 0036-5548 (Print) Linking ISSN: 00365548 NLM ISO Abbreviation: Scand J Infect Dis Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: 2007-2014 : London : Informa Healthcare Original Publication: Stockholm, Society for the Publication of Acta medica Scandinavica. |
| مواضيع طبية MeSH: | Bacteremia/*complications , IgA Vasculitis/*complications , Pneumococcal Infections/*complications, Disseminated Intravascular Coagulation/complications ; Humans ; Hypotension/complications ; Male ; Middle Aged ; Syndrome |
| مستخلص: | Purpura fulminans is classically defined by ecchymotic skin lesions, fever, and hypotension. The majority of cases occur in association with bacterial sepsis, and disseminated intravascular coagulation (DIC) is usually present. Prompted by our experience with a patient with pneumococcal sepsis and purpura fulminans in whom hypotension was never observed, we evaluated the important parameters of sepsis in reports of this syndrome. 42 additional cases of pneumococcal bacteremia and purpura fulminans were identified. Hypotension was present in only 51%. Although DIC was present in 85% of patients, hypofibrinogenemia was documented in only 26%. By contrast, both hypotension and hypofibrinogenemia are present in the vast majority of patients described with purpura fulminans in association with meningococcal sepsis. These data confirm that hypotension is not a necessary feature of the syndrome of purpura fulminans associated with pneumococcal sepsis and suggest further that qualitative or quantitative differences exist in the DIC cascade of pneumococcal vs meningococcal sepsis. |
| Number of References: | 41 |
| تواريخ الأحداث: | Date Created: 19970101 Date Completed: 19980203 Latest Revision: 20211203 |
| رمز التحديث: | 20231215 |
| DOI: | 10.3109/00365549709011858 |
| PMID: | 9435036 |
| قاعدة البيانات: | MEDLINE |
PDF full text from Publisher | تدمد: | 0036-5548 |
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| DOI: | 10.3109/00365549709011858 |