دورية أكاديمية
Assessment of brain perfusion in coma and comparison between SPECT and CT scan data: preliminary report.
| العنوان: | Assessment of brain perfusion in coma and comparison between SPECT and CT scan data: preliminary report. |
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| المؤلفون: | Facco E; Department of Anesthesiology and Intensive Care, University of Padua, Italy., Munari M, Behr AU, Baratto BF, Zucchetta P, Bui F, Cesaro S, Giron GP |
| المصدر: | Neurological research [Neurol Res] 1998; Vol. 20 Suppl 1, pp. S40-3. |
| نوع المنشور: | Comparative Study; Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Taylor & Francis Country of Publication: England NLM ID: 7905298 Publication Model: Print Cited Medium: Print ISSN: 0161-6412 (Print) Linking ISSN: 01616412 NLM ISO Abbreviation: Neurol Res Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: 2016- : Abingdon : Taylor & Francis Original Publication: New York, Crane, Russak. |
| مواضيع طبية MeSH: | Tomography, Emission-Computed, Single-Photon* , Tomography, X-Ray Computed*, Brain/*blood supply , Coma/*diagnostic imaging, Adolescent ; Adult ; Aged ; Cerebrovascular Circulation ; Coma/therapy ; Cysteine/analogs & derivatives ; Female ; Humans ; Male ; Middle Aged ; Organotechnetium Compounds ; Persistent Vegetative State/diagnostic imaging ; Persistent Vegetative State/therapy ; Pilot Projects ; Radiopharmaceuticals ; Technetium Tc 99m Exametazime ; Treatment Outcome ; Xenon Radioisotopes |
| مستخلص: | In this study we submitted 24 comatose patients (Glasgow Coma Score <8) to Single Photon Emission Tomography (SPECT) during the clinical course of coma to verify its utility and the relationship between SPECT and CT scan data. SPECT was recorded following i.v. injection of Xe-133 in 17 patients and of Tc-99m-HMPAO or Tc-99m-ECD in the remaining 7. SPECT data recorded during the acute phase of coma did not show a clear correlation between cerebral blood flow (CBF) and outcome. SPECT and CT scan detected abnormalities in the same areas in 6 cases (25%); 6 patients (25%) with focal CT-scan lesions showed no focal CBF alterations in the same regions; conversely, in the remaining 12 cases (50%) SPECT disclosed severe perfusion abnormalities where no lesions were detectable on CT-scan. SPECT allowed us to recognize different regional flow patterns, such as absolute or relative hyperemia or oligoemia, which could not be checked with other means, thus improving patient's management. Apart from cerebral ischemia, there was no relationship between lesions on CT-scan and flow pattern. Our preliminary results suggest that SPECT can improve both the knowledge of patient's neurological conditions and management in comparison to the use of only CT scan. |
| المشرفين على المادة: | 0 (Organotechnetium Compounds) 0 (Radiopharmaceuticals) 0 (Xenon Radioisotopes) 3B744AG22N (Technetium Tc 99m Exametazime) H25WJA31XE (technetium Tc 99m bicisate) K848JZ4886 (Cysteine) |
| تواريخ الأحداث: | Date Created: 19980519 Date Completed: 19980615 Latest Revision: 20190921 |
| رمز التحديث: | 20221213 |
| DOI: | 10.1080/01616412.1998.11740608 |
| PMID: | 9584923 |
| قاعدة البيانات: | MEDLINE |
PDF full text from Publisher | تدمد: | 0161-6412 |
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| DOI: | 10.1080/01616412.1998.11740608 |