دورية أكاديمية
Cutaneous lesions in swine after decompression: histopathology and ultrastructure.
| العنوان: | Cutaneous lesions in swine after decompression: histopathology and ultrastructure. |
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| المؤلفون: | Buttolph TB; Naval Medical Research Institute, Bethesda, Maryland 20889-5607, USA., Dick EJ Jr, Toner CB, Broome JR, Williams R, Kang YH, Wilt NL |
| المصدر: | Undersea & hyperbaric medicine : journal of the Undersea and Hyperbaric Medical Society, Inc [Undersea Hyperb Med] 1998 Summer; Vol. 25 (2), pp. 115-21. |
| نوع المنشور: | Journal Article; Research Support, U.S. Gov't, Non-P.H.S. |
| اللغة: | English |
| بيانات الدورية: | Publisher: Undersea and Hyperbaric Medical Society Country of Publication: United States NLM ID: 9312954 Publication Model: Print Cited Medium: Print ISSN: 1066-2936 (Print) Linking ISSN: 10662936 NLM ISO Abbreviation: Undersea Hyperb Med Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: Bethesda, Md. : Undersea and Hyperbaric Medical Society Original Publication: Bethesda, Md. : The Society, c1993- |
| مواضيع طبية MeSH: | Decompression Sickness/*pathology , Skin Diseases/*pathology, Animals ; Disease Models, Animal ; Diving/adverse effects ; Male ; Skin/ultrastructure ; Skin Diseases, Vascular/pathology ; Swine |
| مستخلص: | A detailed histopathologic description of skin lesions from a porcine model of decompression sickness (DCS) is presented. Pigs were dived in a dry chamber on a variety of profiles over an 11-mo period, with a 0.1-0.6 (10-60%) incidence of cutaneous lesions. The clinical appearance of the lesions evolved from irregular, sharply demarcated areas of erythema to violaceous and, eventually, darkly mottled macules. The lesions were biopsied under deep, sedative anesthesia. Histologic abnormalities were found in 91% (20/22) of the biopsies from clinically apparent cutaneous lesions. Vascular congestion was the most common finding. Focal areas of vasculitis were noted in 45% (10/22) of the lesions. Perivascular neutrophil infiltrates, edema, and occasionally, hemorrhage were also noted. Ultrastructural abnormalities were found in all of the lesions studied. Acute inflammation affecting the dermal vasculature was the most common finding. Platelets were rarely observed aggregating within vessels. The clinical and histologic features of cutaneous lesions in pigs after decompression are compared with previous accounts in humans. The model provides a useful tool for the study of cutaneous lesions in DCS and may be a means of exploring interventions in the disease. |
| تواريخ الأحداث: | Date Created: 19980722 Date Completed: 19980810 Latest Revision: 20061115 |
| رمز التحديث: | 20221213 |
| PMID: | 9670437 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 1066-2936 |
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