دورية أكاديمية
Use of exogenous hormones hormones and risk of papillary thyroid cancer (Washington, United States).
| العنوان: | Use of exogenous hormones hormones and risk of papillary thyroid cancer (Washington, United States). |
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| المؤلفون: | Rossing MA; Program in Epidemiology, Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA 98104, USA., Voigt LF, Wicklund KG, Williams M, Daling JR |
| المصدر: | Cancer causes & control : CCC [Cancer Causes Control] 1998 May; Vol. 9 (3), pp. 341-9. |
| نوع المنشور: | Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S. |
| اللغة: | English |
| بيانات الدورية: | Publisher: Kluwer Academic Publishers Country of Publication: Netherlands NLM ID: 9100846 Publication Model: Print Cited Medium: Print ISSN: 0957-5243 (Print) Linking ISSN: 09575243 NLM ISO Abbreviation: Cancer Causes Control Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: Dordrecht : Kluwer Academic Publishers Original Publication: Oxford, UK : Rapid Communications of Oxford Ltd., 1990- |
| مواضيع طبية MeSH: | Carcinoma, Papillary/*etiology , Contraceptives, Oral, Hormonal/*adverse effects , Estrogen Replacement Therapy/*adverse effects , Thyroid Neoplasms/*etiology, Adolescent ; Adult ; Age Factors ; Carcinoma, Papillary/epidemiology ; Female ; Humans ; Middle Aged ; Odds Ratio ; Risk Factors ; Thyroid Neoplasms/epidemiology ; Washington/epidemiology |
| مستخلص: | Objectives: Greater incidence of thyroid cancer in women than men, particularly evident during the reproductive years, has led to the suggestion that female hormones may increase risk of this disease. We conducted a population-based case-control study in women aged 18 to 64 years in three counties of western Washington State (United States) to assess the relation of use of exogenous hormones, including oral contraceptives (OC) and hormone replacement therapy (HRT), to risk of papillary thyroid cancer. Methods: Of 558 women with thyroid cancer of the follicular epithelium diagnosed during 1988-94 who were identified as eligible, 468 (83.9 percent) were interviewed; this analysis was restricted to women with papillary histology (n = 410). Controls (n = 574) were identified by random digit dialing, with a response proportion of 73.6 percent. Logistic regression was used to calculate odds ratios (OR) and associated 95 percent confidence intervals (CI) estimating the relative risk of papillary thyroid cancer among users of exogenous hormones. Results: Among women aged 45 to 64 years, we observed no association of use of OCs or HRT with risk of papillary thyroid cancer. Among women less than 45 years of age, risk of papillary thyroid cancer was reduced in women who had ever used OCs (OR = 0.6, CI = 0.4-0.9); beyond the relation with ever-use, there was no further association with specific aspects of exposure such as estrogenic potency, latency, recency, age at first or last use, or use at the reference date. Conclusions: Our data do not support the hypothesis that use of exogenous estrogens increases the risk of female thyroid cancer. |
| معلومات مُعتمدة: | N01-CN-05230 United States CN NCI NIH HHS; R01 CA52656 United States CA NCI NIH HHS |
| المشرفين على المادة: | 0 (Contraceptives, Oral, Hormonal) |
| تواريخ الأحداث: | Date Created: 19980731 Date Completed: 19980924 Latest Revision: 20191024 |
| رمز التحديث: | 20231215 |
| DOI: | 10.1023/a:1008833422577 |
| PMID: | 9684714 |
| قاعدة البيانات: | MEDLINE |
Find this article in full text from Springer Verlag. 
Full Text Finder | تدمد: | 0957-5243 |
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| DOI: | 10.1023/a:1008833422577 |