دورية أكاديمية
Variations in white blood count, thromboxane B2 levels and hematocrit in chronic venous hypertension.
| العنوان: | Variations in white blood count, thromboxane B2 levels and hematocrit in chronic venous hypertension. |
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| المؤلفون: | Guimarães PC; Vascular Surgery Service, Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo, Brazil. pguimara@uol.com.br, Puech-Leão P, Netto BM, Wolosker N, Aun R, Yamamoto LU |
| المصدر: | Sao Paulo medical journal = Revista paulista de medicina [Sao Paulo Med J] 1998 May-Jun; Vol. 116 (3), pp. 1721-6. |
| نوع المنشور: | Clinical Trial; Comparative Study; Controlled Clinical Trial; Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Associação Paulista de Medicina Country of Publication: Brazil NLM ID: 100897261 Publication Model: Print Cited Medium: Print ISSN: 1516-3180 (Print) Linking ISSN: 15163180 NLM ISO Abbreviation: Sao Paulo Med J Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: São Paulo, S.P., Brazil : Associação Paulista de Medicina, [1994- |
| مواضيع طبية MeSH: | Hematocrit* , Leukocyte Count*, Thromboxane B2/*blood , Varicose Ulcer/*blood, Adolescent ; Adult ; Female ; Humans ; Male ; Middle Aged ; Prospective Studies ; Thromboxane B2/metabolism ; Varicose Ulcer/metabolism |
| مستخلص: | Objective: To analyze variations in leukocyte count and thromboxane B2 production in the femoral vein of patients with chronic venous hypertension (CVH). Design: Prospective clinical study, controlled, non randomized and open. Location: Hospital das Clínicas, Faculdade de Medicina da Universidade de São Paulo, referral center, university hospital. Participants: 15 patients with recurring stasis ulcer were analyzed, selected randomly from the venous diseases outpatient center, and 4 without lower limb venous alterations were also analyzed. Intervention: Blood samples from the femoral and brachial veins were drawn following supine and 45 degrees reverse Trendelenburg. Main Outcomes Measures: Direct leukocyte count and analysis of the thromboxane B2 with enzyme linked immunosorbent assay test. Results: After 30 minutes in reverse Trendelenburg, patients with CVH showed a leukocyte count reduced by +/- 27% (p = 0.02) and thromboxane B2 levels increased by +/- 158% (p = 0.02). Conclusions: We suggest that future studies of medications for stasis ulcers include their effects on leukocyte entrapment and thromboxane B2 production in the lower limb venous system. |
| المشرفين على المادة: | 54397-85-2 (Thromboxane B2) |
| تواريخ الأحداث: | Date Created: 19990107 Date Completed: 19990325 Latest Revision: 20190921 |
| رمز التحديث: | 20240829 |
| DOI: | 10.1590/s1516-31801998000300006 |
| PMID: | 9876450 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 1516-3180 |
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| DOI: | 10.1590/s1516-31801998000300006 |