دورية أكاديمية
Lithogenic risk factors in the urine of black and white subjects.
| العنوان: | Lithogenic risk factors in the urine of black and white subjects. |
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| المؤلفون: | Whalley NA; Department of Medicine, Johannesburg Hospital, South Africa., Moraes MF, Shar TG, Pretorius SS, Meyers AM |
| المصدر: | British journal of urology [Br J Urol] 1998 Dec; Vol. 82 (6), pp. 785-90. |
| نوع المنشور: | Journal Article; Research Support, Non-U.S. Gov't |
| اللغة: | English |
| بيانات الدورية: | Publisher: Blackwell Science Country of Publication: England NLM ID: 15740090R Publication Model: Print Cited Medium: Print ISSN: 0007-1331 (Print) Linking ISSN: 00071331 NLM ISO Abbreviation: Br J Urol Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: -1998: Oxford : Blackwell Science Original Publication: London, E & S Livingstone. |
| مواضيع طبية MeSH: | Black People* , White People*, Diet/*adverse effects , Urinary Calculi/*urine, Adult ; Calcium, Dietary/administration & dosage ; Citric Acid/urine ; Female ; Humans ; Incidence ; Male ; Oxalates/administration & dosage ; Oxalates/urine ; Phosphates/urine ; Potassium/urine ; Risk Factors ; Sodium/urine ; South Africa/epidemiology ; Urinary Calculi/ethnology ; Urinary Calculi/etiology |
| مستخلص: | Objective: To identify biochemical and dietary factors which may play a role in the low incidence of stone formation in the black South African population. Subjects and Methods: The study included 31 semiurbanized black and 29 urbanized white subjects. The protocol and modern laboratory techniques used to assess recurrent stone formers were followed. Urinary sodium, potassium, creatinine, calcium, phosphate and urate levels were measured, and urinary citrate, oxalate and cystine assessed. Results: Black subjects ate a diet significantly higher in sodium (P < 0.04); there was no difference in serum levels but urinary sodium was significantly higher (P < 0.001) in black than in white subjects. Urinary potassium, calcium, citrate, phosphate and cystine were all significantly lower in black than in white subjects (P < 0.001 for the first four and P < 0.03 for cystine). Conclusion: Certain intrinsic factors in South African black subjects may account for their lower frequency of stone formation than in white subjects. Of these, the very low urinary calcium, decreased urinary cystine and different interactions between sodium and calcium/cystine are probably important. |
| المشرفين على المادة: | 0 (Calcium, Dietary) 0 (Oxalates) 0 (Phosphates) 2968PHW8QP (Citric Acid) 9NEZ333N27 (Sodium) RWP5GA015D (Potassium) |
| تواريخ الأحداث: | Date Created: 19990112 Date Completed: 19990121 Latest Revision: 20221207 |
| رمز التحديث: | 20240627 |
| DOI: | 10.1046/j.1464-410x.1998.00877.x |
| PMID: | 9883212 |
| قاعدة البيانات: | MEDLINE |
| تدمد: | 0007-1331 |
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| DOI: | 10.1046/j.1464-410x.1998.00877.x |