التفاصيل البيبلوغرافية
| العنوان: |
Plasma zinc α2-glycoprotein levels are elevated in smokers and correlated with metabolic syndrome. |
| المؤلفون: |
Tsai, Jaw‐Shiun, Chen, Su‐Chiu, Huang, Kuo‐Chin, Lue, Bee‐Horng, Lee, Long‐Teng, Chiu, Tai‐Yuan, Chen, Ching‐Yu, Guo, Fei‐Ran, Chuang, Lee‐Ming |
| المصدر: |
European Journal of Clinical Investigation; May2015, Vol. 45 Issue 5, p452-459, 8p |
| مصطلحات موضوعية: |
METABOLIC syndrome risk factors, PHYSIOLOGICAL effects of tobacco, BLOOD plasma, ZINC in the body, GLYCOPROTEINS, MULTIPLE regression analysis |
| مستخلص: |
Background Smoking is a strong risk factor of metabolic syndrome. Zinc α2-glycoprotein ( ZAG) is a protein involved in metabolic syndrome. This study aims to investigate the effect of smoking on plasma ZAG levels and its relations to metabolic syndrome. Materials and methods A group of 41 cigarette smokers and 47 non-smokers were enrolled. ZAG levels were measured to correlate to participants' demographic and metabolic parameters. Results Plasma ZAG levels of smokers were higher than those of controls ( P < 0·0001). Plasma ZAG levels were positively correlated with male gender ( P = 0·0002), number of cigarettes smoked per day ( P < 0·0001), smoking duration in years ( P < 0·0001), smoking index ( P < 0·0001) and nicotine dependence score ( P < 0·0001). In the multiple regression analysis, smoking was a strong independent factor affecting plasma ZAG levels ( P = 0·0034). Plasma ZAG levels elevated progressively with the number of metabolic syndrome components ( P = 0·0143 ). In the multiple regression analysis, plasma ZAG was an independent factor for metabolic syndrome. Conclusions Plasma ZAG levels are high in smokers and correlate with metabolic syndrome. Our results indicate ZAG is an independent risk factor, but also interacted with smoking, for the metabolic syndrome. [ABSTRACT FROM AUTHOR] |
|
Copyright of European Journal of Clinical Investigation is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) |
| قاعدة البيانات: |
Complementary Index |
Full Text Finder