التفاصيل البيبلوغرافية
| العنوان: |
Prevalence of scarred and dysfunctional myocardium in patients with heart failure of ischaemic origin: a cardiovascular magnetic resonance study. |
| المؤلفون: |
Bourantas CV, Nikitin NP, Loh HP, Lukaschuk EI, Sherwi N, de Silva R, Tweddel AC, Alamgir MF, Wong K, Gupta S, Clark AL, Cleland JG |
| المصدر: |
Journal of Cardiovascular Magnetic Resonance (BioMed Central); 2011, Vol. 13 Issue 1, p11p-11p, 1p |
| مستخلص: |
BACKGROUND:Cardiovascular magnetic resonance (CMR) with late gadolinium enhancement (LGE) can provide unique data on the transmural extent of scar/viability. We assessed the prevalence of dysfunctional myocardium, including partial thickness scar, which could contribute to left ventricular contractile dysfunction in patients with heart failure and ischaemic heart disease who denied angina symptoms.METHODS:We invited patients with ischaemic heart disease and a left ventricular ejection fraction < 50% by echocardiography to have LGE CMR. Myocardial contractility and transmural extent of scar were assessed using a 17-segment model.RESULTS:The median age of the 193 patients enrolled was 70 (interquartile range: 63-76) years and 167 (87%) were men. Of 3281 myocardial segments assessed, 1759 (54%) were dysfunctional, of which 581 (33%) showed no scar, 623 (35%) had scar affecting 50% of wall thickness. Of 1522 segments with normal contractile function, only 98 (6%) had evidence of scar on CMR. Overall, 182 (94%) patients had >/=1 and 107 (55%) patients had >/=5 segments with contractile dysfunction that had no scar or 50% of the wall thickness affected by scar, suggesting that most dysfunctional segments could improve in response to an appropriate intervention. [ABSTRACT FROM AUTHOR] |
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| قاعدة البيانات: |
Complementary Index |
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