دورية أكاديمية

Hantavirus pulmonary syndrome, central plateau, southeastern, and southern Brazil.

التفاصيل البيبلوغرافية
العنوان: Hantavirus pulmonary syndrome, central plateau, southeastern, and southern Brazil.
المؤلفون: Figueiredo LT, Moreli ML, de-Sousa RL, Borges AA, de-Figueiredo GG, Machado AM, Bisordi I, Nagasse-Sugahara TK, Suzuki A, Pereira LE, de-Souza RP, de-Souza LT, Braconi CT, Harsi CM, de-Andrade-Zanotto PM, Viral Diversity Genetic Network Consortium, Figueiredo, Luiz T M, Moreli, Marcos L, de-Sousa, Ricardo L M, Borges, Alessandra A
المصدر: Emerging Infectious Diseases; Apr2009, Vol. 15 Issue 4, p561-567, 7p
مستخلص: Hantavirus pulmonary syndrome (HPS) is an increasing health problem in Brazil because of encroachment of sprawling urban, agricultural, and cattle-raising areas into habitats of subfamily Sigmodontinae rodents, which serve as hantavirus reservoirs. From 1993 through June 2007, a total of 884 cases of HPS were reported in Brazil (case-fatality rate 39%). To better understand this emerging disease, we collected 89 human serum samples and 68 rodent lung samples containing antibodies to hantavirus from a 2,500-km-wide area in Brazil. RNA was isolated from human samples and rodent tissues and subjected to reverse transcription-PCR. Partial sequences of nucleocapsid protein and glycoprotein genes from 22 human and 16 rodent sources indicated only Araraquara virus and Juquitiba virus lineages. The case-fatality rate of HPS was higher in the area with Araraquara virus. This virus, which may be the most virulent hantavirus in Brazil, was associated with areas that have had greater anthropogenic changes. [ABSTRACT FROM AUTHOR]
Copyright of Emerging Infectious Diseases is the property of Centers for Disease Control & Prevention (CDC) and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
قاعدة البيانات: Complementary Index
الوصف
تدمد:10806040
DOI:10.3201/eid1504.080289