التفاصيل البيبلوغرافية
| العنوان: |
Surface-etching enhances titanium implant osseointegration in newly formed (rhBMP-2-induced) and native bone. |
| المؤلفون: |
Qahash M, Hardwick WR, Rohrer MD, Wozney JM, Wikesjö UME |
| المصدر: |
International Journal of Oral & Maxillofacial Implants; May/Jun2007, Vol. 22 Issue 3, p472-477, 6p |
| مستخلص: |
PURPOSE: The influence of surface modifications on osseointegration in newly formed bone is not well established. The purpose of this study was to compare osseointegration at acid-etched versus turned implants in newly formed and native bone. METHODS: Supra-alveolar peri-implant defects were created in 8 hound/Labrador mongrel dogs. Titanium implants 10 mm long (2 turned and 1 dual acid-etched) were placed 5 mm into the surgically reduced alveolar crest, creating 5-mm supra-alveolar peri-implant defects. Recombinant human bone morphogenetic protein-2 (rhBMP-2; 0.4 mg) in a collagen carrier was used to induce new bone formation. A macroporous, expanded polytetrafluoroethylene device was used to delineate new bone formation. The animals were euthanized at 8 weeks for histometric analysis of the experimental sites. RESULTS: There were no significant differences in rhBMP-2-induced bone density (mean +/- SD) at acid-etched versus turned implants (20.6% +/- 5.3% vs 23.8% +/- 4.7%; P = .232). However, there was a significant difference in bone-implant contact in favor of the acid-etched implants (12.3% +/- 6.8% vs 7.9% +/- 3.1%; P = .05). Native bone density averaged 63.9% +/- 7.5% and 64.5% +/- 9.0% for acid-etched and turned implants, respectively (P = .641). Nevertheless, bone-implant contact was significantly enhanced at acid-etched versus turned implants (59.7% +/- 11.3% vs 40.7% +/-21.2%; P =.005). CONCLUSIONS: Surface dual acid-etching of titanium implants has a positive effect on osseointegration in newly formed and native bone. Significant differences in bone density do not appear to influence this effect. [ABSTRACT FROM AUTHOR] |
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| قاعدة البيانات: |
Complementary Index |
