التفاصيل البيبلوغرافية
| العنوان: |
Bilateral lower extremity gangrene requiring amputation associated with heparin-induced thrombocytopenia -- a case report. |
| المؤلفون: |
Dickinson BP, De Ugarte DA, Reil TD, Beseth BD, Lawrence PF |
| المصدر: |
Vascular & Endovascular Surgery; Mar/Apr2006, Vol. 40 Issue 2, p161-164, 4p |
| مستخلص: |
Heparin use, both prophylactically and therapeutically, is prevalent among hospitalized patients. Patients on heparin may develop a thrombocytopenia that is self-limited. Fewer patients develop a heparin-induced thrombocytopenia that can cause severe bleeding and thrombosis owing to intravascular platelet aggregation. The authors present a case report of heparin-induced thrombocytopenia in a patient who underwent aortic arch and aortic valve replacement that resulted in bilateral above-knee amputations. The patient developed limb ischemia related to heparin-associated thrombosis, but had a delay in antibody seroconversion. Early and accurate diagnosis of heparin-induced thrombocytopenia requires a high clinical suspicion and may be present despite the absence of serum antibodies. [ABSTRACT FROM AUTHOR] |
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| قاعدة البيانات: |
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