التفاصيل البيبلوغرافية
| العنوان: |
Synthesis, Biophysical, and Biochemical Properties of PNA-DNA Chimeras. |
| المؤلفون: |
Bajor, Zoltán, Sági, Gyula, Tegyey, Zsuzsanna, Ötvös, László |
| المصدر: |
Nucleosides, Nucleotides & Nucleic Acids; May2003, Vol. 22 Issue 5-8, p1215-1217, 3p |
| مصطلحات موضوعية: |
NUCLEASES, EXONUCLEASES, BIOCHEMISTRY, DNA, HYDROLYSIS |
| مستخلص: |
Three PNA-DNA chimeric dimer synthons (tT, upT and uhT, see Sch. 1) have been synthesized in solution and used to make T20-analogue chimeras applying standard solid-phase DNA synthesis protocol. Duplex forming ability of chimeras with dA20 and their hydrolyses by 3′- and 5′-exonucleases (snake venom and bovine spleen phosphodiesterase, respectively) have been investigated. [ABSTRACT FROM AUTHOR] |
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| قاعدة البيانات: |
Complementary Index |
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