التفاصيل البيبلوغرافية
| العنوان: |
Life-threatening bradyarrhythmia with oral phenytoin overdose. |
| المؤلفون: |
Srinivasan, Giridharan, Wyawahare, Mukta, Mathen, Pratheesh George, Subrahmanyam, Dharanipragada K. |
| المصدر: |
Journal of Pharmacology & Pharmacotherapeutics; Jul-Sep2015, Vol. 6 Issue 3, p179-181, 3p |
| مصطلحات موضوعية: |
ARRHYTHMIA treatment, PHENYTOIN, DRUG overdose, GLIBENCLAMIDE, CARDIOTOXICITY |
| مستخلص: |
We report a case of a 41-year-old lady, who developed severe hypotension and sinus bradycardia, following oral consumption of 20 g of phenytoin and 500 mg of glibenclamide. She required high dose of inotropes and a temporary transvenous pacer for her hemodynamic instability. This life-threatening cardiotoxicity of phenytoin could have been due to its interaction with sulphonylurea. It is imperative to be aware of drug interactions, due to which, life-threatening cardiovascular manifestations following phenytoin toxicity can occur. [ABSTRACT FROM AUTHOR] |
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| قاعدة البيانات: |
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