التفاصيل البيبلوغرافية
| العنوان: |
Prolonged hepatitis and jaundice: a rare complication of paediatric Epstein-Barr virus infection. |
| المؤلفون: |
Zhen Han Tan, Kong Boo Phua, Ong, Christina, Kader, Ajmal |
| المصدر: |
Singapore Medical Journal; Jul2015, Vol. 56 Issue 7, pe112-e115, 4p |
| مصطلحات موضوعية: |
HEPATITIS in children, DISEASE complications, ULTRASONIC imaging, HEPATOMEGALY |
| مستخلص: |
We herein report the case of a 14-year-old girl with Epstein-Barr virus (EBV) infectious mononucleosis who developed prolonged hepatitis and jaundice. At presentation, she had tender hepatomegaly with a markedly deranged liver function test. Abdominal ultrasonography showed hepatomegaly and a thickened gallbladder wall. During the subsequent 11 weeks, her transaminases showed twofurther peaks, which corresponded with clinical deterioration. Her highest alanine transaminase level was 1,795 μ/L and total bilirubin level was 154 μmol/L. She recovered fully with conservative management. EBV-related liver involvement is typically mild and self-limiting. We believe that tender hepatomegaly and gallbladder thickening may be important predictors of significant liver involvement. Although multiple transaminase peaks may occur, we do not consider this an indication for antiviral or immunosuppressive therapy. In the absence of strong evidence supporting the use of any specific therapy, we recommend a conservative approach for an immunocompetent patient. [ABSTRACT FROM AUTHOR] |
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| قاعدة البيانات: |
Complementary Index |
