التفاصيل البيبلوغرافية
| العنوان: |
Genetic Damage Induced by a Food Coloring Dye (Sunset Yellow) on Meristematic Cells of Brassica campestris L. |
| المؤلفون: |
Dwivedi, Kshama, Kumar, Girjesh |
| المصدر: |
Journal of Environmental & Public Health; 4/14/2015, Vol. 2015, p1-5, 5p |
| مصطلحات موضوعية: |
COLORING matter in food, DYES & dyeing, MERISTEMS, TURNIPS, PLANT cells & tissues, ARTIFICIAL foods |
| مستخلص: |
We have performed the present piece of work to evaluate the effect of synthetic food coloring azo dye (sunset yellow) on actively dividing root tip cells of Brassica campestris L. Three doses of azo dye were administered for the treatment of actively dividing root tip cells, namely, 1%, 3%, and 5%, for 6-hour duration along with control. Mitotic analysis clearly revealed the azo dye induced endpoint deviation like reduction in the frequency of normal divisions in a dose dependent manner. Mitotic divisions in the control sets were found to be perfectly normal while dose based reduction in MI was registered in the treated sets. Azo dye has induced several chromosomal aberrations (genotoxic effect) at various stages of cell cycle such as stickiness of chromosomes, micronuclei formation, precocious migration of chromosome, unorientation, forward movement of chromosome, laggards, and chromatin bridge. Among all, stickiness of chromosomes was present in the highest frequency followed by partial genome elimination as micronuclei. The present study suggests that extensive use of synthetic dye should be forbidden due to genotoxic and cytotoxic impacts on living cells. Thus, there is an urgent need to assess potential hazardous effects of these dyes on other test systems like human and nonhuman biota for better scrutiny. [ABSTRACT FROM AUTHOR] |
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| قاعدة البيانات: |
Complementary Index |
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