التفاصيل البيبلوغرافية
| العنوان: |
Gender differences in depressive symptom profiles and patterns of psychotropic drug usage in Asian patients with depression: Findings from the Research on Asian Psychotropic Prescription Patterns for Antidepressants study. |
| المؤلفون: |
Park, Seon-Cheol, Lee, Min-Soo, Shinfuku, Naotaka, Sartorius, Norman, Park, Yong Chon |
| المصدر: |
Australian & New Zealand Journal of Psychiatry; Sep2015, Vol. 49 Issue 9, p833-841, 9p |
| مصطلحات موضوعية: |
ANTIDEPRESSANTS, DIAGNOSIS of mental depression, ANTIPSYCHOTIC agents, PSYCHIATRIC drugs, ANALYSIS of covariance, CHI-squared test, MENTAL depression, DRUG prescribing, PROBABILITY theory, PSYCHOTHERAPY patients, SEX distribution, SUBSTANCE abuse, T-test (Statistics), COMORBIDITY, PHYSICIAN practice patterns, LOGISTIC regression analysis, ASIANS, DATA analysis software, DESCRIPTIVE statistics, ODDS ratio, PSYCHOLOGY |
| مصطلحات جغرافية: |
CHINA, INDIA, INDONESIA, JAPAN, KOREA, MALAYSIA, SINGAPORE, TAIWAN, THAILAND, HONG Kong (China) |
| مستخلص: |
Objectives: The purpose of this study was to investigate whether there were gender-specific depressive symptom profiles or gender-specific patterns of psychotropic agent usage in Asian patients with depression. Method: Clinical data from the Research on Asian Psychotropic Prescription Patterns for Antidepressant study (1171 depressed patients) were used to determine gender differences by analysis of covariates for continuous variables and by logistic regression analysis for discrete variables. In addition, a binary logistic regression model was fitted to identify independent clinical correlates of the gender-specific pattern on psychotropic drug usage. Results: Men were more likely than women to have loss of interest (adjusted odds ratio = 1.379, p = 0.009), fatigue (adjusted odds ratio = 1.298, p = 0.033) and concurrent substance abuse (adjusted odds ratio = 3.793, p = 0.008), but gender differences in other symptom profiles and clinical features were not significant. Men were also more likely than women to be prescribed adjunctive therapy with a second-generation antipsychotic (adjusted odds ratio = 1.320, p = 0.044). However, men were less likely than women to have suicidal thoughts/acts (adjusted odds ratio = 0.724, p = 0.028). Binary logistic regression models revealed that lower age (odds ratio = 0.986, p = 0.027) and current hospitalization (odds ratio = 3.348, p < 0.0001) were independent clinical correlates of use of second-generation antipsychotics as adjunctive therapy for treating depressed Asian men. Conclusion: Unique gender-specific symptom profiles and gender-specific patterns of psychotropic drug usage can be identified in Asian patients with depression. Hence, ethnic and cultural influences on the gender preponderance of depression should be considered in the clinical psychiatry of Asian patients. [ABSTRACT FROM AUTHOR] |
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| قاعدة البيانات: |
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