التفاصيل البيبلوغرافية
| العنوان: |
Comparative Susceptibility of Aedes albopictus and Aedes aegypti to Dengue Virus Infection After Feeding on Blood of Viremic Humans: Implications for Public Health. |
| المؤلفون: |
Whitehorn, James, Hue Kien, Duong Thi, Nguyen, Nguyet Minh, Nguyen, Hoa L., Kyrylos, Peter P., Carrington, Lauren B., Bich Tran, Chau Nguyen, Ha Quyen, Nguyen Thanh, Long Vo Thi, Dui Le Thi, Nguyen Thanh Truong, Tai Thi Hue Luong, Chau Van Vinh Nguyen, Wills, Bridget, Wolbers, Marcel, Simmons, Cameron P., Kien, Duong Thi Hue, Tran, Chau Nguyen Bich, Quyen, Nguyen Thanh Ha, Thi, Long Vo |
| المصدر: |
Journal of Infectious Diseases; 10/15/2015, Vol. 212 Issue 8, p1182-1190, 9p |
| مصطلحات موضوعية: |
AEDES albopictus, AEDES aegypti, DENGUE, PUBLIC health, INFECTIOUS disease transmission, ODDS ratio, CONFIDENCE intervals, FLAVIVIRUSES, ANIMAL experimentation, DISEASE vectors, DISEASE susceptibility, MOSQUITOES, RESEARCH funding, VIREMIA, PHYSIOLOGY |
| مصطلحات جغرافية: |
VIETNAM |
| مستخلص: |
Aedes albopictus is secondary to Aedes aegypti as a vector of dengue viruses (DENVs) in settings of endemicity, but it plays an important role in areas of dengue emergence. This study compared the susceptibility of these 2 species to DENV infection by performing 232 direct blood-feeding experiments on 118 viremic patients with dengue in Vietnam. Field-derived A. albopictus acquired DENV infections as readily as A. aegypti after blood feeding. Once infected, A. albopictus permitted higher concentrations of DENV RNA to accumulate in abdominal tissues, compared with A. aegypti. However, the odds of A. albopictus having infectious saliva were lower than the odds observed for A. aegypti (odds ratio, 0.70; 95% confidence interval, .52-.93). These results quantitate the susceptibility of A. albopictus to DENV infection and will assist parameterization of models for predicting disease risk in settings where A. albopictus is present. [ABSTRACT FROM AUTHOR] |
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| قاعدة البيانات: |
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