التفاصيل البيبلوغرافية
| العنوان: |
Comparative study on the antimicrobial activity of partitioned fractions of the stem-bark of ceiba pentandra (bombacaceae). |
| المؤلفون: |
N. S., Njinga, M. I., Sule, U. U., Pateh, H. S., Hassan, R. N., Ache, S. T., Abdullahi, B. A., Danja |
| المصدر: |
Nitte University Journal of Health Science; Dec2015, Vol. 5 Issue 4, p4-8, 5p |
| مصطلحات موضوعية: |
ANTI-infective agents, MALVACEAE, DRUG resistance in bacteria, ETHYL acetate, BUTANOL |
| مستخلص: |
Due to the emergence of more and more drug resistance bacteria and the reported antibacterial activity of Ceiba pentandra, the antimicrobial activity of the partitioned ethyl-acetate and n-butanol fractions of the stem-bark of this plant were carried out on the following clinical isolates: Staphylococcus aureus; Streptococcus pyrogenes; corynebacterium ulcereans; Escherichia coli; Salmonella typhi; Shigella dysenterea; Enterococcus aerogenes; Pseudomonas aeruginosa; klebsiella pneumonia and the fungi Trichophytom rubrum, Microsporum sp., Aspergillus fumigatus and Aspergillus niger. Agar diffusion and broth delusion methods were used in this study. The ethyl acetate fraction showedwide spectrumantibacteria activity (with zones of inhibition between 27mmand 37mm)while the n-butanol extract showed activity only against the gram negative bacteria (zones of inhibition between 20mmand 21mm). The MIC ranged from0.65 to 2.5mg/ml and 2.5 to 5mg/ml andMBC ranged from2.5mg/ml and 5 - 10mg/ml for the ethylacetate and n-butanol respectively. Both fractions showed no activity against the fungi used in this study. The preliminary phytochemistry of the ethyl acetate showed the presence of only flavonoid and thismay explain the activity against all the bacteria. The n-butanol showed the presence of carbohydrates, saponins, tannins and cardiac glycoside and the absence of flavonoid and alkaloids. This study justifies the use of this plant in herbalmedicine. [ABSTRACT FROM AUTHOR] |
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| قاعدة البيانات: |
Complementary Index |
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