التفاصيل البيبلوغرافية
| العنوان: |
Specialization versus conservation: How Pol I and Pol III use the conserved architecture of the pre-initiation complex for specialized transcription. |
| المؤلفون: |
Hoffmann, Niklas A., Sadian, Yashar, Tafur, Lucas, Kosinski, Jan, Müller, Christoph W. |
| المصدر: |
Transcription (2154-1264); 2016, Vol. 7 Issue 4, p127-132, 6p |
| مصطلحات موضوعية: |
RNA polymerase III, RNA polymerase I, EUKARYOTIC genomes, TRANSCRIPTION factors, MOLECULAR structure of enzymes |
| مستخلص: |
Here, we discuss the overall architecture of the RNA polymerase I (Pol I) and III (Pol III) core enzymes and their associated general transcription factors in the context of models of the Pol I and Pol III pre-initiation complexes, thereby highlighting potential functional adaptations of the Pol I and Pol III enzymes to their respective transcription tasks. Several new insights demonstrate the great degree of specialization of each of the eukaryotic RNA polymerases that is only beginning to be revealed as the structural and functional characterization of all eukaryotic RNA polymerases and their pre-initiation complexes progresses. [ABSTRACT FROM PUBLISHER] |
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Copyright of Transcription (2154-1264) is the property of Taylor & Francis Ltd and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) |
| قاعدة البيانات: |
Complementary Index |
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