التفاصيل البيبلوغرافية
| العنوان: |
The intra- and inter-individual variability and reliability of transepidermal water loss measurements. |
| المؤلفون: |
Pinnagoda, Jaliya, Tupker, Ron A., Smit, Jet A., Coenraads, Pieter J., Nater, Johan P. |
| المصدر: |
Contact Dermatitis (01051873); Oct89, Vol. 21 Issue 4, p255-259, 5p |
| مصطلحات موضوعية: |
CONTACT dermatitis, EPIDEMIOLOGY, HUMAN body, SKIN inflammation, ALLERGIES |
| مستخلص: |
An analysis of variance was conducted to estimate the intra- and inter-individual variations in TEWL on the forearms, by sites (8 measurement sites) and by days (10 different days), in 30 non-exposed healthy individuals. The estimated intra and inter-individual variations, by sites, were 15.5% and 84.5%. respectively, the sum of the 2 components always being 100%. With the exclusion or the 2 most distal sites near the wrist, which had significantly higher baseline TEWL values and fluctuations in TEWL, an improvement in the intra-individual variation was obtained Thus, of the 6 sites, the estimated intra- and inter-individual variations were 8.4% and 91.6%, respectively. This finding supports the exclusion of these most distal sites for future investigations. The estimated intra- and inter-individual variations, by days, were 20.6% and 79.4%, respectively. The low site-to-site (8.4%) and day-to-day (20.6%) intra-individual variations, as compared to the large inter-individual variations of the same (91.6% and 79.4%), indicate that baseline TEWL is a stable personal characteristic Thus, individuals susceptible to irritant contact dermatitis (ICD), due to occupational exposure. may be reliably characterized by utilizing their baseline TEWL values, for "prediction" of risk in epidemiological field studies. [ABSTRACT FROM AUTHOR] |
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| قاعدة البيانات: |
Complementary Index |
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