التفاصيل البيبلوغرافية
| العنوان: |
In(OTf)3 assisted synthesis of β-carboline C-3 tethered imidazo[1,2-a]azine derivatives. |
| المؤلفون: |
Devi, Nisha, Singh, Dharmender, Kaur, Gurpreet, Mor, Satbir, Putta, V. P. R. Kishore, Polina, Saibabu, Malakar, Chandi C., Singh, Virender |
| المصدر: |
New Journal of Chemistry; 1/30/2017, Vol. 41 Issue 3, p1082-1093, 12p |
| مصطلحات موضوعية: |
INDIUM, CARBOLINES, CHEMICAL synthesis, IMIDAZOLES |
| مستخلص: |
Synthesis of β-carboline based natural products and synthetic derivatives is one of the frontier areas of research owing to their medicinal properties. It is envisaged that 3-formyl-9H-β-carboline is a potential precursor and offers new vistas for the construction of a variety of heterocyclic architectures at the C-3 position of the β-carboline skeleton. In this context, an efficient protocol has been developed for the synthesis of β-carboline C-3 tethered imidazo[1,2-a]pyridine, imidazo[1,2-a]pyrimidine, and imidazo[1,2-a]pyrazine derivatives via exploration of the Groebke–Blackburn–Bienayme (GBB) reaction. The present protocol offers several advantages like operational simplicity, high atom economy, appreciable structural diversity and easy purification procedure. [ABSTRACT FROM AUTHOR] |
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