التفاصيل البيبلوغرافية
| العنوان: |
Declining Trends of Cardiovascular-Renal Complications and Mortality in Type 2 Diabetes: The Hong Kong Diabetes Database. |
| المؤلفون: |
Luk, Andrea O. Y., Hui, Eric M. T., Ming-Chuen Sin, Chun-Yip Yeung, Wing-Sun Chow, Ho, Andrew Y. Y., Hin-Fai Hung, Kan, Eva, Chiu-Ming Ng, Wing-Yee So, Chi-Kin Yeung, Kin-Sang Chan, Kin-Wah Chan, Pang-Fai Chan, Shing-Chung Siu, Sau-Cheung Tiu, Yeung, Vincent T. F., Chan, Juliana C. N., Chan, Frank W. K., Cheung, Clement |
| المصدر: |
Diabetes Care; Jul2017, Vol. 40 Issue 7, p928-935, 8p |
| مصطلحات موضوعية: |
DIABETES complications, DIABETES, TYPE 2 diabetes, MYOCARDIAL infarction, STROKE |
| مستخلص: |
Objective: Nationwide studies on secular trends of diabetes complications are not available in Asia. We examined changes in risk factor control and incidence of complications from diabetes and death in a large longitudinal cohort of Chinese adults with type 2 diabetes in Hong Kong.Research Design and Methods: Between 1 January 2000 and 31 December 2012, 338,908 Chinese adults with type 2 diabetes underwent metabolic and complication assessment in 16 diabetes centers operated by Hong Kong Hospital Authority that provided care to a large majority of diagnosed patients. Patients were followed for incident acute myocardial infarction (AMI), stroke, end-stage renal disease (ESRD), and death until 31 December 2012. Risk factor levels between enrollment periods were compared. Incidence of clinical events, stratified by diabetes duration, was examined over time.Results: Incidence of complications from diabetes and death declined over the observation period in patients at varying disease duration. Among the high-risk group with diabetes for at least 15 years, crude incidence of AMI decreased from 8.7 to 5.8, stroke from 13.5 to 10.1, ESRD from 25.8 to 22.5, and death from 29.0 to 26.6 per 1,000 person-year between the periods 2000 to 2002 and 2010 to 2012. Improvements in levels of metabolic risk factors were detected. Proportion of patients achieving HbA1c <7.0% (53 mmol/mol) was increased from 32.9 to 50.0%, blood pressure ≤130/80 mmHg from 24.7 to 30.7%, and LDL cholesterol <2.6 mmol/L from 25.8 to 38.1%.Conclusions: From this territory-wide Hong Kong Diabetes Database, we observed decreases in incidence of cardiovascular-renal complications and death and corresponding improvements in risk factor control over a 13-year period. [ABSTRACT FROM AUTHOR] |
|
Copyright of Diabetes Care is the property of American Diabetes Association and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) |
| قاعدة البيانات: |
Complementary Index |
