التفاصيل البيبلوغرافية
| العنوان: |
Mortality of neonatal respiratory failure from Chinese northwest NICU network. |
| المؤلفون: |
Zhang, L., Qiu, Y., Yi, B., Ni, L., Zhang, L, Taxi, Pulati, Li, H., Zhang, Q., Wang, W., Liu, Z., Li, L., Zhao, L., Wang, H., Sun, B. |
| المصدر: |
Journal of Maternal-Fetal & Neonatal Medicine; Sep2017, Vol. 30 Issue 17, p2105-2111, 7p |
| مصطلحات موضوعية: |
RESPIRATORY distress syndrome, NEONATAL death, HYPOXEMIA, INTENSIVE care units, RESPIRATORY insufficiency in children, COMORBIDITY, HEALTH of Chinese people, RESPIRATORY distress syndrome treatment, RESPIRATORY insufficiency treatment, PULMONARY surfactant, ARTIFICIAL respiration, LOW birth weight, GESTATIONAL age, PREMATURE infants, LONGITUDINAL method, NEONATAL intensive care, RESPIRATORY insufficiency, RESUSCITATION, NEONATAL intensive care units, DISEASE incidence, ECONOMICS, THERAPEUTICS |
| مصطلحات جغرافية: |
CHINA |
| مستخلص: |
Objectives: We aimed to evaluate the efficacy of respiratory support and surfactant in incidence, management and outcome of neonatal hypoxemic respiratory failure (NRF) in Chinese emerging regional neonatal-perinatal care system in the era of universal health insurance policy.Study Design: Clinical data of NRF were prospectively collected in 12 consecutive months from 2011 to 2012 in 12 neonatal intensive care units (NICU) in major cities of Northwest China. NRF was defined as hypoxemia requiring nasal continuous positive airway pressure (nCPAP) or intratracheal ventilation combined with surfactant for at least 24 h, with associated risk factors, mortality rate and major co-morbidities analyzed.Results: Among 9816 admissions, there were 1324 NRF cases with 60.2% being preterm. The incidence of NRF was 13.4% with a mortality of 15.5%. The major underlying diseases were respiratory distress syndrome (RDS, 38.9%) and pneumonia/sepsis (38.0%). Only 15.9% of NRF and 33.8% of RDS received surfactant, which contributed to >70% and >85% survival in RDS patients of birth weight (BW) < 1500 g and >1500 g, respectively. Multivariate logistic regression analysis showed that premature rupture of membrane ≥ 24 h, very low BW and gestational age < 32 weeks, resuscitation at delivery, illness severity at admission, intratracheal ventilation and sepsis were the independent risk factors for the mortality of NRF. The length and cost of NICU stay for survivors reflected care burden in the era of universal health insurance.Conclusions: Surfactant significantly improved the survival of neonates with NRF and RDS, reflecting the respiratory care standard in emerging regional neonatal-perinatal care network with limited resources. [ABSTRACT FROM AUTHOR] |
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| قاعدة البيانات: |
Complementary Index |
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