التفاصيل البيبلوغرافية
| العنوان: |
The Effects of Travel Burden on Outcomes After Resection of Extrahepatic Biliary Malignancies: Results from the US Extrahepatic Biliary Consortium. |
| المؤلفون: |
O'Connor, Sean, Mogal, Harveshp, Russell, Gregory, Ethun, Cecilia, Fields, Ryan, Jin, Linda, Hatzaras, Ioannis, Vitiello, Gerardo, Idrees, Kamran, Isom, Chelsea, Martin, Robert, Scoggins, Charles, Pawlik, Timothy, Schmidt, Carl, Poultsides, George, Tran, Thuy, Weber, Sharon, Salem, Ahmed, Maithel, Shishir, Shen, Perry |
| المصدر: |
Journal of Gastrointestinal Surgery; Dec2017, Vol. 21 Issue 12, p2016-2024, 9p |
| مصطلحات موضوعية: |
SURGICAL excision, GERM cell tumors, CANCER patients, INFLAMMATION, PATHOLOGY, HOSPITALS, INCOME, MEDICAL care, RESEARCH funding, SURVIVAL, TRAVEL, BILE duct tumors, SPECIALTY hospitals, TREATMENT effectiveness, PROPORTIONAL hazards models, RETROSPECTIVE studies |
| مصطلحات جغرافية: |
UNITED States |
| مستخلص: |
Background: Surgical resection of extrahepatic biliary malignancies has been increasingly centralized at high-volume tertiary care centers. While this has improved outcomes overall, increased travel burden has been associated with worse survival for many other malignancies. We hypothesized that longer travel distances are associated with worse outcomes for these patients as well.Study Design: Data was analyzed from the US Extrahepatic Biliary Consortium database, which retrospectively reviewed patients who received resection of extrahepatic biliary malignancies at 10 high-volume centers. Driving distance to the patient's treatment center was measured for 1025 patients. These were divided into four quartiles for analysis: < 24.5, 24.5-57.2, 57.2-117, and < 117 mi. Cox proportional hazard models were then used to measure differences in overall survival.Results: No difference was found between the groups in severity of disease or post-operative complications. The median overall survival in each quartile was as follows: 1st = 1.91, 2nd = 1.60, 3rd = 1.30, and 4th = 1.39 years. Patients in the 3rd and 4th quartile had a significantly lower median household income (p = 0.0001) and a greater proportion Caucasian race (p = 0.0001). However, neither of these was independently associated with overall survival. The two furthest quartiles were found to have decreased overall survival (HR = 1.39, CI = 1.12-1.73 and HR = 1.3, CI = 1.04-1.62), with quartile 3 remaining significant after multivariate analysis (HR = 1.45, CI = 1.04-2.0, p = 0.028).Conclusions: Longer travel distances were associated with decreased overall survival, especially in the 3rd quartile of our study. Patients traveling longer distances also had a lower household income, suggesting that these patients have significant barriers to care. [ABSTRACT FROM AUTHOR] |
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| قاعدة البيانات: |
Complementary Index |
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