التفاصيل البيبلوغرافية
| العنوان: |
Reference Intervals of Cytokeratin-19 Fragment (CYFRA 21-1) in Healthy Adults in China. |
| المؤلفون: |
Yunhai Dai, Wei Qu, Shibiao Sang, Shaoneng Tao, Yan Li, Yan Wang, Qingru Li, Tingting Wu, Anyou Zhu, Qing Chen, Jiaqi Song, Qing Li, Yongliang Ji, Yijie Zheng, Fengchao Wang |
| المصدر: |
Clinical Laboratory; 2018, Vol. 64, p123-133, 11p |
| مصطلحات موضوعية: |
KERATIN, BLOOD testing, URINALYSIS, KIDNEY function tests, LIVER function tests, CHINESE people |
| مستخلص: |
Background: The reference intervals for serum cytokeratin-19 fragment (CYFRA 21-1) have not been established in Chinese population. This study aimed to measure serum CYFRA 21-1 levels in healthy Chinese subjects. Methods: This cross-sectional, four-center study in two Chinese provinces enrolled participants (aged 18 - 85 years) with normal liver/kidney function and normal results for routine blood tests/urinalysis. Serum CYFRA 21-1 level was measured by ARCHITECT immunoassay (Abbott Diagnostics). Results: The study included 3,366 participants. The median (interquartile range) value for serum CYFRA 21-1 level was 1.38 (1.00 - 1.89) ng/mL and tended to increase with age. The upper limit of the 97.5th percentile was 3.55 ng/mL and tended to increase with age. Serum CYFRA 21-1 median level varied between the four centers from 1.22 (0.89, 1.71) to 1.55 (1.12, 2.18) ng/mL, while the 97.5th percentile varied from 3.24 to 4.09 ng/mL. CYFRA 21-1 level correlated weakly with age and creatinine level. Conclusions: These new data can help to establish the 'normal range' of serum CYFRA 21-1 in people in China. [ABSTRACT FROM AUTHOR] |
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| قاعدة البيانات: |
Complementary Index |
