التفاصيل البيبلوغرافية
| العنوان: |
THE CORRELATION BETWEEN BODY MASS INDEX AND THYROID STIMULATING HORMONE IN EUTHYROID PERSONS. |
| Alternate Title: |
KORELACIJA INDEKSA MASE TELA I STIMULIRAJUCEG HORMONA ŠTITNE ŽLEZDE KOD EUTIREOIDNIH OSOBA. (Bosnian) |
| المؤلفون: |
Dimić, Dragan, Velojić-Golubović, Milena, Radenković, Saša |
| المصدر: |
Acta Medica Medianae; Mar2018, Vol. 57 Issue 1, p33-37, 5p |
| مصطلحات موضوعية: |
BODY mass index, THYROID hormones, THYROID diseases |
| Abstract (English): |
The aim of the study was to determine the correlation between body mass index (BMI), thyroid stimulating hormone (TSH), and thyroid hormones in euthyroid persons. The study included 396 euthyroid participants. The subjects with already established disease of the thyroid function were excluded. In all subjects we measured weight, height and determined BMI. According to BMI values, the subjests were divided into three groups: group A - BMI up to 24.9 (normal weight); group B - BMI from 25 to 29.9 (overweight); group C - BMI over 30 (obesity). In all subjests we determined serum TSH and free thyroxine (FT4) levels and antibodies to thyroid peroxidase (TPOAb). According to TSH levels, the subjects were divided into two groups: TSH up to 2.5, and TSH higher than 2.5. There is an increase in TSH levels with increasing of BMI. In group C, TSH values were significantly higher than in the groups A and B, and were also higher than the mean values of TSH in all subjects. TSH level in group B were slightly higher compared to the group A but there is no statistically significant difference. TPOAb values increase with increasing of BMI. The mean value of BMI was significantly lower in the group of patients with TSH values lower than 2.5, compared to the mean value of BMI in the group of patients with TSH values higher than 2.5. The relationship of BMI and TSH points to significant positive correlations of two parameters, except in group A. We found a significant degree of positive correlation between BMI and TSH, which remains within the normal range. There are also significant changes in the of TPOAb values. There is no significant changes in the FT4 levels. [ABSTRACT FROM AUTHOR] |
| Abstract (Bosnian): |
Cilj rada bio je utvrditi korelaciju između indeksa telesne mase (body mass index, BMI), stimulirajućeg hormona štitne žlezde (TSH) i tireoidnih hormona kod eutireoidnih osoba. U ispitivanje je uključeno 396 eutiroidnih osoba. Nisu uključene osobe sa poznatim oboljenjem tiroidne funkcije. Kod svih ispitanika izmerena je telesna težina i visina i određen BMI. Prema vrednostima BMI podeljeni su u tri grupe; do 24,9 normalno uhranjeni, grupa A; od 25-29,9 sa prekomernom težinom, grupa B i preko 30 gojaznih, grupa C. Kod svih ispitanika su određivane vrednosti serumskog TSH, slobodnog tiroksina (FT4) i antitela na tiroidnu peroksidazu (TPOab). Prema vrednostima TSH ispitanici su podeljeni u dve grupe, TSH do 2,5 i preko 2,5. Zapaža se porast vrednosti TSH sa porastom BMI. Vrednosti TSH su statistički značajno veće u grupi C u odnosu na grupu A i B, kao i u odnosu na srednje vrednosti TSH svih ispitanika. Vrednosti TSH u grupi B su nešto veće o odnosu na grupu A, ali nema statistički značajne razlike. Vrednosti TPOab rastu sa porastom BMI. Srednja vrednost BMI je značajno niža u grupi ispitanika sa vrednostima TSH manjim od 2,5 u odnosu na srednju vrednost BMI u grupi ispitanika sa vrednostima TSH većim od 2,5. Odnos BMI i TSH pokazuje pozitivnost korelacije dva parametra, osim u grupi A. Utvrdili smo značajan stepen pozitivne korelacije BMI i TSH, koji ostaje u okviru granica normalnih vrednosti. Postoje i značajne promene vrednosti TPOab. Nema značajnih promena vrednosti FT4. [ABSTRACT FROM AUTHOR] |
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