التفاصيل البيبلوغرافية
| العنوان: |
Diagnostic assessment of haemorrhagic rash and fever. |
| المؤلفون: |
Nielsen, H. E., Andersen, E. A., Andersen, J., Böttiger, B., Christiansen, K. M., Daugbjerg, P., Larsen, S. O., Lind, I., Nir, M., Olofsson, K. |
| المصدر: |
Archives of Disease in Childhood; Aug2001, Vol. 85 Issue 2, p160-165, 6p |
| مصطلحات موضوعية: |
NEISSERIA meningitidis, ENTEROVIRUS diseases, HEMORRHAGIC fever, HEMORRHAGIC diseases, SKIN diseases, ALGORITHMS |
| مستخلص: |
Aims-To establish criteria for early distinction between meningococcal disease and other conditions with similar clinical features, and to identify other causes for haemorrhagic rashes accompanied by fever. Methods-In a prospective study, 264 infants and children hospitalised with fever and skin haemorrhages were studied. Results-We identified an aetiological agent in 28%: 15% had meningococcal disease, 2% another invasive bacterial infection, 7% enterovirus infection, and 4% adenovirus infection. Five clinical variables distinguished between meningococcal disease and other conditions on admission: (1) skin haemorrhages of characteristic appearance; (2) universal distribution of skin haemorrhages; (3) maximum diameter of one or more skin haemorrhages greater than 2 mm; (4) poor general condition (using a standardised observation scheme); and (5) nuchal rigidity. If any two or more of these clinical variables were present, the probability of identifying a patient with meningococcal disease was 97% and the false positive rate was only 12%. This diagnostic algorithm did not identify children in whom septicaemia was caused by other bacterial species. [ABSTRACT FROM AUTHOR] |
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| قاعدة البيانات: |
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