التفاصيل البيبلوغرافية
| العنوان: |
Evaluation of the quality of prescription of antibiotics with curative intent in a specialized department in Dakar, Senegal. |
| المؤلفون: |
N. M., Dia, Y. Z., Ismail, N. A., Lakhe, B. M., Diop, M., Seydi |
| المصدر: |
International Journal of Medicine & Biomedical Research; Jan-Apr2018, Vol. 7 Issue 1, p21-31, 11p |
| مصطلحات موضوعية: |
ANTIBIOTICS, CURATIVE medicine, PROFESSIONAL practice, ANTITUBERCULAR agents, DRUG resistance |
| مستخلص: |
Background: Evaluation of professional practices is a way of contributing to improvement of prescription. Our work aimed at assessing quality of antibiotics prescription with curative intent (excluding treatment containing anti-TB drugs) in a clinic of infectious diseases in Dakar. Methods: A prospective and observational study was conducted from April 2 to July 2, 2012 in all hospitalized patients aged 15 years and older who received antibiotic treatment with curative intent. Quality of prescription was evaluated according to national recommendations of PRONALIN which served as a reference. Thus two levels of appreciation, appropriate and inappropriate were used. Results: From 02/04/2012 to 02/07/2012, 316 patients were hospitalized in the department, of which 170 (53.79%) received antibiotic therapy. During this period, 267 antibiotic prescriptions were made. The main identified infections were pneumonia (28.3%). Monotherapy was received by 57.70% of patients. The most prescribed antibiotic families were ß-lactams (55.43%) mostly ceftriaxone. The first antibiotics combination use was amoxicillinclavulanate- spiramycin (37.66%). Antibiotic therapy was probabilistic in 155 (91.18%) and documented in 15 (8.82%). Compliance rate of antibiotic prescription to national recommendations was 74.7%. Prescriptions according to molecules were appropriate in 97.37%, dosages adequate in 90.63% and routes of administration well observed in 98.87%. Duration of treatment was not appropriate in 119 cases (44.56%). Only 15.9% of antibiotic therapy was assessed at 48 hours. Conclusion: Compliance rate of antibiotic prescription to national recommendations was 74.7% in this specialized department of Dakar, mainly due to non-respected treatment times and lack of evaluation of antibiotic therapy after 48 Hours. [ABSTRACT FROM AUTHOR] |
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| قاعدة البيانات: |
Complementary Index |
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